Nucleosomes compact and organize genetic material on a structural level. However, they
also alter local chromatin accessibility through changes in their position, through the …

Influenza viruses hijack host cell factors at each stage of the viral life cycle. After host cell
entry and endosomal escape, the influenza viral ribonucleoproteins (vRNPs) are released …

The retrovirus human immunodeficiency virus-1 (HIV-1) is the causative agent of AIDS.
Although treatment of HIV/AIDS with antiretroviral therapy provides suppression of viremia …

Although there are several pathways to ensure that proteins are folded properly in the cell,
little is known about the molecular mechanisms regulating histone folding and proteostasis …

SET is a multifunctional oncoprotein which is ubiquitously expressed in all kinds of cells. The
SET protein participates in many cellular processes including cell cycle, cell migration …

RCOR1 is a known transcription repressor that recruits and positions LSD1 and HDAC1/2
on chromatin to erase histone methylation and acetylation. However, there is currently an …

Genetic disruption of synaptic proteins results in a whole variety of human neuropsychiatric
disorders including intellectual disability, schizophrenia or autism spectrum disorder (ASD) …

High-mobility group box 1 (HMGB1) can enhance the stability and accessibility of nucleus
binding sites to nucleosomes and transcription factors. Recently, HMGB1 has been …

The rice blast fungus Magnaporthe oryzae poses a great threat to global food security.
During its conidiation (asexual spore formation) and appressorium (infecting structure) …

Viral immune evasion is crucial to the pathogenesis of hepatitis B virus (HBV) infection.
However, the role of HBV in the modulation of innate immune evasion is poorly understood …