Astragaloside IV acts through multi-scale mechanisms to effectively reduce diabetic nephropathy

E Wang, L Wang, R Ding, M Zhai, R Ge, P Zhou… - Pharmacological …, 2020 - Elsevier
Diabetic nephropathy (DN), a common complication of diabetes mellitus, is the main cause
of end-stage nephropathy, and thus developing novel strategies for reversing DN remains …

A Comprehensive Review on Potential In Silico Screened Herbal Bioactive Compounds and Host Targets in the Cardiovascular Disease Therapy

E Zarenezhad, AT Hadi, E Nournia… - BioMed Research …, 2024 - Wiley Online Library
Herbal medicines (HMs) have deciphered indispensable therapeutic effects against
cardiovascular disease (CVD)(the predominant cause of death worldwide). The …

Molecular combination networks in medicinal plants: understanding synergy by network pharmacology in Indian traditional medicine

PK Mukherjee, S Banerjee, A Kar - Phytochemistry Reviews, 2021 - Springer
Translation of traditional medicine is moving away from the reductionist approach towards
harnessing the synergy of poly-pharmacological phyto-combinations that modulate the …

A network pharmacology integrated pharmacokinetics strategy for uncovering pharmacological mechanism of compounds absorbed into the blood of Dan-Lou tablet …

M Ding, W Ma, X Wang, S Chen, S Zou, J Wei… - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacological relevance Dan-Lou tablet (DLT) is developed from the
traditional Chinese medicine (TCM) formula Gualou Xiebai Baijiu Tang which has been …

Integration of metabolomics and transcriptomics to reveal anti-chronic myocardial ischemia mechanism of Gualou Xiebai decoction

F Zhang, B Duan, Z Zhou, L Han, P Huang, Y Ye… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Gualou Xiebai decoction (GLXB), a well-known
classic traditional Chinese medicine formula, is a recorded and proven therapy for the …

The chemical and metabolite profiles of Gualou-Xiebai-Banxia decoction, a classical traditional Chinese medicine formula, by using high-performance liquid …

Z Xiang, Y Wang, S Liu - Journal of Ethnopharmacology, 2022 - Elsevier
Abstract Ethnopharmacological relevance Gualou-Xiebai-Banxia decoction (GXBD) was a
classical traditional Chinese medicine formula for the treatment of coronary heart disease …

Systems pharmacology reveals the multi-level synergetic mechanism of action of Ginkgo biloba L. leaves for cardiomyopathy treatment

Y Li, C Xu, H Wang, X Liu, L Jiang, S Liang… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Cardiomyopathy is a common cause of heart failure and
may lead to increased risk of sudden cardiac death, lacking simple, safe and effective …

Network Pharmacology‐Based Investigation of the System‐Level Molecular Mechanisms of the Hematopoietic Activity of Samul‐Tang, a Traditional Korean Herbal …

HS Lee, IH Lee, SI Park, DY Lee - … ‐Based Complementary and …, 2020 - Wiley Online Library
Hematopoiesis is a dynamic process of the continuous production of diverse blood cell types
to meet the body's physiological demands and involves complex regulation of multiple …

Characterization of volatile organic compounds with anti-atherosclerosis effects in Allium macrostemon Bge. and Allium chinense G. Don by head space solid phase …

Z Qin, S Duan, Y Li, X Li, H Xing, Z Yao, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Introduction Allium macrostemon Bge.(AMB) and Allium chinense G. Don (ACGD) are both
edible Allium vegetables and named officinal Xiebai (or Allii Macrostemonis Bulbus) in East …

Gualou xiebai decoction ameliorates cardiorenal syndrome type II by regulation of PI3K/AKT/NF-κB signalling pathway

Y Wang, Y Liu, J Li, Y Zhang, Y Ding, Y Peng - Phytomedicine, 2024 - Elsevier
Background Cardiorenal syndromes type II (CRS2) is a multi-organ ailment that manifests as
a combination of cardiac and renal dysfunction, resulting in chronic kidney disease due to …