Exposure to air pollution as a potential contributor to cognitive function, cognitive decline, brain imaging, and dementia: a systematic review of epidemiologic research
Background Dementia is a devastating condition typically preceded by a long prodromal
phase characterized by accumulation of neuropathology and accelerated cognitive decline …
phase characterized by accumulation of neuropathology and accelerated cognitive decline …
[HTML][HTML] Statistical methods for mediation analysis in the era of high-throughput genomics: current successes and future challenges
Mediation analysis investigates the intermediate mechanism through which an exposure
exerts its influence on the outcome of interest. Mediation analysis is becoming increasingly …
exerts its influence on the outcome of interest. Mediation analysis is becoming increasingly …
Fine particulate air pollution and the expression of microRNAs and circulating cytokines relevant to inflammation, coagulation, and vasoconstriction
Background: MicroRNAs (miRNAs) are a key factor in epigenetic regulation of gene
expression, but miRNA responses to fine particulate matter (PM 2.5) air pollution and their …
expression, but miRNA responses to fine particulate matter (PM 2.5) air pollution and their …
Long-term exposure to ambient fine particulate matter and renal function in older men: the veterans administration normative aging study
Background: It is unknown if ambient fine particulate matter (PM2. 5) is associated with lower
renal function, a cardiovascular risk factor. Objective: We investigated whether long-term …
renal function, a cardiovascular risk factor. Objective: We investigated whether long-term …
B vitamins attenuate the epigenetic effects of ambient fine particles in a pilot human intervention trial
Acute exposure to fine particle (PM2. 5) induces DNA methylation changes implicated in
inflammation and oxidative stress. We conducted a crossover trial to determine whether B …
inflammation and oxidative stress. We conducted a crossover trial to determine whether B …
Particulate air pollution and fasting blood glucose in nondiabetic individuals: associations and epigenetic mediation in the normative aging study, 2000–2011
Background: Among nondiabetic individuals, higher fasting blood glucose (FBG)
independently predicts diabetes risk, cardiovascular disease, and dementia. Ambient PM2 …
independently predicts diabetes risk, cardiovascular disease, and dementia. Ambient PM2 …
Causal mediation analysis of survival outcome with multiple mediators
Background: Mediation analyses have been a popular approach to investigate the effect of
an exposure on an outcome through a mediator. Mediation models with multiple mediators …
an exposure on an outcome through a mediator. Mediation models with multiple mediators …
DNA methylation mediates the association between breastfeeding and early-life growth trajectories
L Briollais, D Rustand, C Allard, Y Wu, J Xu… - Clinical …, 2021 - Springer
Background The role of breastfeeding in modulating epigenetic factors has been suggested
as a possible mechanism conferring its benefits on child development but it lacks evidence …
as a possible mechanism conferring its benefits on child development but it lacks evidence …
Does logistics influence economic growth? The European experience
Purpose The purpose of this paper is to set forth a new economic model that includes
variables that take account the mediator effect of global competitiveness index to better …
variables that take account the mediator effect of global competitiveness index to better …
[HTML][HTML] Short-term exposure to fine particulate matter and its constituents may affect renal function via oxidative stress: A longitudinal panel study
Exposure to fine particulate matter (PM 2. 5) has been reported to increase the risks of
chronic kidney disease. However, limited research has assessed the effect of PM 2.5 and its …
chronic kidney disease. However, limited research has assessed the effect of PM 2.5 and its …