Recent advances in microfluidic technology for bioanalysis and diagnostics

SF Berlanda, M Breitfeld, CL Dietsche… - Analytical …, 2020 - ACS Publications
Microfluidics has become a mature technology, providing an excellent toolbox for the
handling and manipulation of fluid samples, suspended cells, and particles. About 30 years …

Recent progress of inertial microfluidic-based cell separation

X Xu, X Huang, J Sun, R Wang, J Yao, W Han, M Wei… - Analyst, 2021 - pubs.rsc.org
Cell separation has consistently been a pivotal technology of sample preparation in
biomedical research. Compared with conventional bulky cell separation technologies …

Machine learning assisted fast prediction of inertial lift in microchannels

J Su, X Chen, Y Zhu, G Hu - Lab on a Chip, 2021 - pubs.rsc.org
Inertial effect has been extensively used in manipulating both engineered particles and
biocolloids in microfluidic platforms. The design of inertial microfluidic devices largely relies …

Cell separations and sorting

MA Witek, IM Freed, SA Soper - Analytical chemistry, 2019 - ACS Publications
The development of new methods and technologies for cell separation, sorting, selection,
isolation, or enrichment (many times the aforementioned terms are used interchangeably) …

A Review of Single‐Cell Pose Adjustment and Puncture

X Guo, Y Zhang, D Jin, M Zhou - Advanced Intelligent Systems, 2022 - Wiley Online Library
Single‐cell manipulation technology is an essential method of cell research, with wide
applications in biological engineering, medical engineering, agricultural engineering, and …

[HTML][HTML] Advances in numerical approaches for microfluidic cell analysis platforms

Z Sheidaei, P Akbarzadeh, N Kashaninejad - Journal of Science: Advanced …, 2020 - Elsevier
Microfluidics has been demonstrating enormous potential through its role in recent
advances in biological sciences. However, designing a new and customized microfluidic …

Rapid fabrication of low-cost thermal bubble-driven micro-pumps

B Hayes, L Smith, H Kabutz, AC Hayes, GL Whiting… - Micromachines, 2022 - mdpi.com
Thermal bubble-driven micro-pumps are an upcoming actuation technology that can be
directly integrated into micro/mesofluidic channels to displace fluid without any moving parts …

Ann-based instantaneous simulation of particle trajectories in microfluidics

N Zhang, K Liang, Z Liu, T Sun, J Wang - Micromachines, 2022 - mdpi.com
Microfluidics has shown great potential in cell analysis, where the flowing path in the
microfluidic device is important for the final study results. However, the design process is …

A self-regulated microfluidic device with thermal bubble micropumps

G Guo, X Wu, D Liu, L Liao, D Zhang, Y Zhang, T Mao… - Micromachines, 2022 - mdpi.com
Currently, many microchips must rely on an external force (such as syringe pump, electro-
hydrodynamic pump, and peristaltic pump, etc.) to control the solution in the microchannels …

Purifying stem cell‐derived red blood cells: a high‐throughput label‐free downstream processing strategy based on microfluidic spiral inertial separation and …

E Guzniczak, O Otto, G Whyte… - Biotechnology and …, 2020 - Wiley Online Library
Cell‐based therapeutics, such as in vitro manufactured red blood cells (mRBCs), are
different to traditional biopharmaceutical products (the final product being the cells …