Computerized clinical decision support systems, or CDSS, represent a paradigm shift in
healthcare today. CDSS are used to augment clinicians in their complex decision-making …

Background Electronic health record (EHR) alert fatigue, while widely recognized as a
concern nationally, lacks a corresponding comprehensive mitigation plan. Objectives The …

Background The clinical decision support system (CDSS) has become an indispensable tool
for reducing medication errors and adverse drug events. However, numerous studies have …

Abstract In 2011, an Institute of Medicine report on health information technology (IT) and
patient safety highlighted that building health-IT for safer use is a shared responsibility …

Background The co-administration of drugs known to interact greatly impacts morbidity,
mortality, and health economics. This study aims to examine the drug–drug interaction (DDI) …

Purpose Current uses of medication-related clinical decision support (CDS) and
recommendations for improving these systems are reviewed. Summary Using a systematic …

A CDSS generates a high number of inappropriate alerts that interrupt the clinical workflow.
As a result, clinicians silence, disable, or ignore alerts, thereby undermining patient safety …

Abstract Objective We describe the Clickbusters initiative implemented at Vanderbilt
University Medical Center (VUMC), which was designed to improve safety and quality and …

Electronic health record (EHR)–based interventions to improve patient safety are complex
and sensitive to who, what, where, why, when, and how they are delivered. Success or …

Introduction There is an increased risk of potential drug–drug interactions (pDDIs) in
critically ill patients based on the number of drugs received. The occurrence of pDDIs and …