Liquid–liquid phase separation is a key organizational principle in eukaryotic cells, on par
with intracellular membranes. It allows cells to concentrate specific proteins into …

Phase separation is the thermodynamic process that explains how droplets form in
multicomponent fluids. These droplets can provide controlled compartments to localize …

Liquid compartments without a surrounding membrane control vital functions and
chemistries in living cells. One subset of droplets regulated by chemical reactions is …

The sustenance of life depends on the high degree of organization that prevails through
different levels of living organisms, from subcellular structures such as biomolecular …

Phase separation is as familiar as watching vinegar separating from oil in vinaigrette. The
observation that phase separation of proteins and nucleic acids is widespread in living cells …

The ParABS system is supposed to be responsible for plasmid partitioning and chromosome
segregation in bacteria. ParABS ensures a high degree of fidelity in inheritance by dividing …

Driven chemical reactions can control the macroscopic properties of droplets, like their size.
Such active droplets are critical in structuring the interior of biological cells. Cells also need …

The purpose of this review is to explore self-organizing mechanisms that pattern
microtubules (MTs) and spatially organize animal cell cytoplasm, inspired by recent …

The genetic material of eukaryotes is segregated into transcriptionally active euchromatin
and silent heterochromatin compartments. The spatial arrangement of chromatin …

Biomolecular assemblies are fundamental to life and viral disease. The spatiotemporal
coordination of viral replication and assembly is largely unknown. Here, we developed a …