[HTML][HTML] Cocrystals by design: a rational coformer selection approach for tackling the API problems
Active pharmaceutical ingredients (API) with unfavorable physicochemical properties and
stability present a significant challenge during their processing into final dosage forms …
stability present a significant challenge during their processing into final dosage forms …
[HTML][HTML] Cocrystal of phloretin with isoniazid: preparation, characterization, and evaluation
Z Lu, H Chen, J Mo, X Yuan, D Wang, X Zheng… - RSC advances, 2023 - pubs.rsc.org
Phloretin (Phl) is a natural flavonoid compound with wide range of biological activities but
demonstrates poor water solubility and limited pharmacological effects. In this study, one …
demonstrates poor water solubility and limited pharmacological effects. In this study, one …
Pharmaceutical Properties of the Phloretin–4, 4′-Bipyridine Cocrystal: Structure Analysis, Drug Release Profile, and Antioxidant Activity Research
Z Lu, G Yao, H Xie, D Wang, Y Chen, W Zhu - ACS Omega, 2024 - ACS Publications
To improve the water solubility of phloretin, we synthesized the Phl–4B cocrystal using the
solvent evaporation method. Various analytical techniques including powder X-ray …
solvent evaporation method. Various analytical techniques including powder X-ray …
[PDF][PDF] Studies on Formulation and Evaluation of Clotrimazole Cocrystals
H Desai, A Rajadhyax, S Jaiswal… - World Journal of …, 2022 - researchgate.net
Cocrystallization uses the approach of hydrogen bonding between a drug and a GRAS
coformer to form a multicomponent crystalline compound with different physicochemical …
coformer to form a multicomponent crystalline compound with different physicochemical …