[HTML][HTML] Glycogen synthase kinase-3 signaling in Alzheimer's disease
E Lauretti, O Dincer, D Praticò - … et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
Alzheimer's disease (AD) is the most common form of neurodegenerative disorder with
dementia, accounting for approximately 70% of the all cases. Currently, 5.8 million people in …
dementia, accounting for approximately 70% of the all cases. Currently, 5.8 million people in …
GSK-3 and Tau: a key duet in Alzheimer's disease
CL Sayas, J Ávila - Cells, 2021 - mdpi.com
Glycogen synthase kinase-3 (GSK-3) is a ubiquitously expressed serine/threonine kinase
with a plethora of substrates. As a modulator of several cellular processes, GSK-3 has a …
with a plethora of substrates. As a modulator of several cellular processes, GSK-3 has a …
Glycogen synthase kinase-3 inhibitors: preclinical and clinical focus on CNS-A decade onward
SM Arciniegas Ruiz, H Eldar-Finkelman - Frontiers in molecular …, 2022 - frontiersin.org
The protein kinase, GSK-3, participates in diverse biological processes and is now
recognized a promising drug discovery target in treating multiple pathological conditions …
recognized a promising drug discovery target in treating multiple pathological conditions …
Novel approaches for the treatment of Alzheimer's and Parkinson's disease
M Van Bulck, A Sierra-Magro, J Alarcon-Gil… - International journal of …, 2019 - mdpi.com
Neurodegenerative disorders affect around one billion people worldwide. They can arise
from a combination of genomic, epigenomic, metabolic, and environmental factors. Aging is …
from a combination of genomic, epigenomic, metabolic, and environmental factors. Aging is …
Donepezil-based multi-functional cholinesterase inhibitors for treatment of Alzheimer's disease
Q Li, S He, Y Chen, F Feng, W Qu, H Sun - European journal of medicinal …, 2018 - Elsevier
Alzheimer's disease (AD) is one of the most common neurodegenerative disorders in elderly
people. Considering the multifactorial nature of AD, the concept of multi-target-directed …
people. Considering the multifactorial nature of AD, the concept of multi-target-directed …
Pivotal role of glycogen synthase kinase-3: a therapeutic target for Alzheimer's disease
Neurodegenerative diseases are among the most challenging diseases with poorly known
mechanism of cause and paucity of complete cure. Out of all the neurodegenerative …
mechanism of cause and paucity of complete cure. Out of all the neurodegenerative …
The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro
JA Morales-García, M De la Fuente Revenga… - Scientific reports, 2017 - nature.com
Banisteriopsis caapi is the basic ingredient of ayahuasca, a psychotropic plant tea used in
the Amazon for ritual and medicinal purposes, and by interested individuals worldwide …
the Amazon for ritual and medicinal purposes, and by interested individuals worldwide …
Differentiation of human mesenchymal stem cells towards neuronal lineage: clinical trials in nervous system disorders
R Hernández, C Jiménez-Luna… - Biomolecules & …, 2019 - pmc.ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have been proposed as an alternative therapy to be
applied into several pathologies of the nervous system. These cells can be obtained from …
applied into several pathologies of the nervous system. These cells can be obtained from …
Roles of microglia in adult hippocampal neurogenesis in depression and their therapeutics
S Fang, Z Wu, Y Guo, W Zhu, C Wan, N Yuan… - Frontiers in …, 2023 - frontiersin.org
Adult hippocampal neurogenesis generates functional neurons from neural progenitor cells
in the hippocampal dentate gyrus (DG) to complement and repair neurons and neural …
in the hippocampal dentate gyrus (DG) to complement and repair neurons and neural …
When good kinases go rogue: GSK3, p38 MAPK and CDKs as therapeutic targets for Alzheimer's and Huntington's disease
SR D'Mello - International Journal of Molecular Sciences, 2021 - mdpi.com
Alzheimer's disease (AD) is a mostly sporadic brain disorder characterized by cognitive
decline resulting from selective neurodegeneration in the hippocampus and cerebral cortex …
decline resulting from selective neurodegeneration in the hippocampus and cerebral cortex …