How to enter a bacterium: bacterial porins and the permeation of antibiotics

JD Prajapati, U Kleinekathöfer… - Chemical …, 2021 - ACS Publications
Despite tremendous successes in the field of antibiotic discovery seen in the previous
century, infectious diseases have remained a leading cause of death. More specifically …

Porins and small-molecule translocation across the outer membrane of Gram-negative bacteria

J Vergalli, IV Bodrenko, M Masi, L Moynié… - Nature Reviews …, 2020 - nature.com
Gram-negative bacteria and their complex cell envelope, which comprises an outer
membrane and an inner membrane, are an important and attractive system for studying the …

Understanding antibiotic resistance via outer membrane permeability

I Ghai, S Ghai - Infection and drug resistance, 2018 - Taylor & Francis
Collective antibiotic drug resistance is a global threat, especially with respect to Gram-
negative bacteria. The low permeability of the bacterial outer cell wall has been identified as …

[HTML][HTML] Antibacterial and antibiotic-modifying activities of three food plants (Xanthosoma mafaffa Lam., Moringa oleifera (L.) Schott and Passiflora edulis Sims) …

JK Dzotam, FK Touani, V Kuete - BMC complementary and alternative …, 2015 - Springer
Background The present study was designed to investigate the antibacterial activities of the
methanol extract of three edible plants, namely Xanthosoma mafaffa, Moringa oleifera and …

[HTML][HTML] Antibacterial activities of selected Cameroonian spices and their synergistic effects with antibiotics against multidrug-resistant phenotypes

AG Fankam, V Kuete, IK Voukeng, JR Kuiate… - … and Alternative Medicine, 2011 - Springer
Background The emergence of multi-drug resistant (MDR) phenotypes is a major public
health problem today in the treatment of bacterial infections. The present study was …

Potential of African medicinal plants against Enterobacteria: Classification of plants antibacterial agents

V Kuete - Advances in Botanical Research, 2023 - Elsevier
In the present chapter, the synopsis of active botanicals and phytochemicals of the flora of
Africa against drug-sensitive and drug-resistant strains of bacteria of the Enterobacteriaceae …

[HTML][HTML] Antibacterial activities of the methanol extracts of Albizia adianthifolia, Alchornea laxiflora, Laportea ovalifolia and three other Cameroonian plants against …

CF Tchinda, IK Voukeng, VP Beng, V Kuete - Saudi journal of biological …, 2017 - Elsevier
In the last 10 years, resistance in Gram-negative bacteria has been increasing. The present
study was designed to evaluate the in vitro antibacterial activities of the methanol extracts of …

[HTML][HTML] Antibacterial activity of nineteen selected natural products against multi-drug resistant Gram-negative phenotypes

AT Mbaveng, LP Sandjo, SB Tankeo, AR Ndifor… - SpringerPlus, 2015 - Springer
The present study was designed to assess the antimicrobial activity of 19 natural products
belonging to terpenoids, alkaloids, thiophenes and phenolics against a panel of 14 Gram …

[HTML][HTML] Antibacterial activity of six medicinal Cameroonian plants against Gram-positive and Gram-negative multidrug resistant phenotypes

IK Voukeng, VP Beng, V Kuete - BMC Complementary and Alternative …, 2016 - Springer
Background Infectious diseases due to multidrug-resistant bacteria are one of the causes of
treatment failures contributing to an increase in mortality and/or morbidity. In this study, we …

[HTML][HTML] A barrier to entry: examining the bacterial outer membrane and antibiotic resistance

I Ghai - Applied Sciences, 2023 - mdpi.com
Gram-negative bacteria can resist antibiotics by changing the permeability via their outer
membrane. These bacteria have a complex cell envelope that incorporates an outer …