Modulation of endothelium function by fatty acids

R Mallick, AK Duttaroy - Molecular and cellular biochemistry, 2022 - Springer
The endothelium acts as the barrier that prevents circulating lipids such as lipoproteins and
fatty acids into the arterial wall; it also regulates normal functioning in the circulatory system …

Para-inflammation in the aging retina

H Xu, M Chen, JV Forrester - Progress in retinal and eye research, 2009 - Elsevier
Para-inflammation is a tissue adaptive response to noxious stress or malfunction and has
characteristics that are intermediate between basal and inflammatory states (Medzhitov …

Macrophage activation by endogenous danger signals

X Zhang, DM Mosser - The Journal of Pathology: A Journal of …, 2008 - Wiley Online Library
Macrophages are cells that function as a first line of defence against invading
microorganisms. One of the hallmarks of macrophages is their ability to become activated in …

Metabolism-associated molecular patterns (MAMPs)

X Wang, Y Wang, V Antony, H Sun, G Liang - Trends in Endocrinology & …, 2020 - cell.com
Metabolic diseases pose a tremendous health threat in both developed and developing
countries. The pathophysiology of metabolic diseases is complex but has been shown to be …

The hydrogen sulfide donor, GYY4137, exhibits anti‐atherosclerotic activity in high fat fed apolipoprotein E−/− mice

Z Liu, Y Han, L Li, H Lu, G Meng, X Li… - British journal of …, 2013 - Wiley Online Library
Background and Purpose Atherosclerosis is associated with reduced vascular hydrogen
sulfide (H2S) biosynthesis. GYY4137 is a novel slow‐releasing H2S compound that may …

Role of 4-hydroxynonenal-protein adducts in human diseases

G Barrera, S Pizzimenti, ES Ciamporcero… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: Oxidative stress provokes the peroxidation of polyunsaturated fatty acids in
cellular membranes, leading to the formation of aldheydes that, due to their high chemical …

Resveratrol mediates anti-atherogenic effects on cholesterol flux in human macrophages and endothelium via PPARγ and adenosine

I Voloshyna, O Hai, MJ Littlefield, S Carsons… - European journal of …, 2013 - Elsevier
Resveratrol is a bioactive molecule used in dietary supplements and herbal medicines and
consumed worldwide. Known cardioprotective and anti-inflammatory properties of …

The lectin-like oxidized low-density-lipoprotein receptor: a pro-inflammatory factor in vascular disease

S Dunn, RS Vohra, JE Murphy… - Biochemical …, 2008 - portlandpress.com
Scavenger receptors are membrane glycoproteins that bind diverse ligands including lipid
particles, phospholipids, apoptotic cells and pathogens. LOX-1 (lectin-like oxidized low …

Age‐related macular degeneration in the aspect of chronic low‐grade inflammation (pathophysiological parainflammation)

M Nita, A Grzybowski, FJ Ascaso… - Mediators of …, 2014 - Wiley Online Library
The products of oxidative stress trigger chronic low‐grade inflammation (pathophysiological
parainflammation) process in AMD patients. In early AMD, soft drusen contain many …

[图书][B] Animal lectins: form, function and clinical applications

GS Gupta - 2012 - books.google.com
Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of
animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular …