Chronic obstructive lung diseases, like asthma and chronic obstructive pulmonary disease,
have high prevalences and are a major public health concern. Chronic obstructive lung …

Asthma and chronic obstructive pulmonary disease (COPD) are both highly prevalent
diseases worldwide. This issue of Clinics in Chest Medicine discusses different aspects of …

Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality worldwide.
We performed a genetic association study in 15,256 cases and 47,936 controls, with …

Background Understanding the genetic basis of airflow obstruction and smoking behaviour
is key to determining the pathophysiology of chronic obstructive pulmonary disease (COPD) …

Because metabolites are hypothesized to play key roles as markers and effectors of
cardiometabolic diseases, recent studies have sought to annotate the genetic determinants …

Although snoring is common in the general population, its aetiology has been largely
understudied. Here we report a genetic study on snoring (n~ 408,000; snorers~ 152,000) …

Rationale: The temporal stability of adult asthma phenotypes identified using clustering
methods has never been addressed. Longitudinal cluster–based methods may provide …

Genes and pathways in which inactivation dampens tissue inflammation present new
opportunities for understanding the pathogenesis of common human inflammatory diseases …

Background Recent meta-analyses of genome-wide association studies in general
populations of European descent have identified 28 loci for lung function. Objective We …

A genetic contribution to develop chronic obstructive pulmonary disease (COPD) is well
established. However, the specific genes responsible for enhanced risk or host differences …