Neisseria meningitidis: using genomics to understand diversity, evolution and pathogenesis

DA Caugant, OB Brynildsrud - Nature Reviews Microbiology, 2020 - nature.com
Meningococcal disease remains an important cause of morbidity and death worldwide
despite the development and increasing implementation of effective vaccines. Elimination of …

Evaluating infectious, neoplastic, immunological, and degenerative diseases of the central nervous system with cerebrospinal fluid-based next-generation sequencing

KI Tsamis, H Sakkas, A Giannakis, HS Ryu… - Molecular Diagnosis & …, 2021 - Springer
Cerebrospinal fluid (CSF) is a clear and paucicellular fluid that circulates within the
ventricular system and the subarachnoid space of the central nervous system (CNS), and …

Multi-omic detection of Mycobacterium leprae in archaeological human dental calculus

AK Fotakis, SD Denham, M Mackie… - … of the Royal …, 2020 - royalsocietypublishing.org
Mineralized dental plaque (calculus) has proven to be an excellent source of ancient
biomolecules. Here we present a Mycobacterium leprae genome (6.6-fold), the causative …

[HTML][HTML] Heterogeneous hunter-gatherer and steppe-related ancestries in Late Neolithic and Bell Beaker genomes from present-day France

A Seguin-Orlando, R Donat, C Der Sarkissian… - Current Biology, 2021 - cell.com
The transition from the Late Neolithic to the Bronze Age has witnessed important population
and societal changes in western Europe. 1 These include massive genomic contributions of …

An invasive Haemophilus influenzae serotype b infection in an Anglo-Saxon plague victim

M Guellil, M Keller, JM Dittmar, SA Inskip, C Cessford… - Genome biology, 2022 - Springer
Abstract Background The human pathogen Haemophilus influenzae was the main cause of
bacterial meningitis in children and a major cause of worldwide infant mortality before the …

Oral metagenomes from native American ancestors reveal distinct microbial lineages in the pre‐contact era

TP Honap, CR Monroe, SJ Johnson… - American Journal of …, 2023 - Wiley Online Library
Objectives Limited studies have focused on how European contact and colonialism
impacted Native American oral microbiomes, specifically, the diversity of commensal or …

Finding archaeological relevance during a pandemic and what comes after

LH Gamble, C Claassen, JW Eerkens, DJ Kennett… - American …, 2021 - cambridge.org
This article emerged as the human species collectively have been experiencing the worst
global pandemic in a century. With a long view of the ecological, economic, social, and …

[HTML][HTML] The role of case studies in recent paleopathological literature: An argument for continuing relevance

AT Boutin, CM Longo, R Lehnhard - International Journal of …, 2022 - Elsevier
Objective To critically examine the role that case studies play in recent paleopathological
literature, by evaluating their frequency of publication, academic impact, and the public …

Identification of microbial pathogens in Neolithic Scandinavian humans

N Bergfeldt, E Kırdök, N Oskolkov, C Mirabello… - Scientific Reports, 2024 - nature.com
With the Neolithic transition, human lifestyle shifted from hunting and gathering to farming.
This change altered subsistence patterns, cultural expression, and population structures as …

Cases of endocranial lesions on juvenile skeletons from Longshan cultural sites in Henan Province, China

L Sun, K Pechenkina, Y Cao, H Zhang, X Qi - International Journal of …, 2019 - Elsevier
Endocranial lesions were recognized on eight out of the 31 juveniles (25.8%) that were
recovered from three Neolithic archaeological sites in Henan province. The remains of …