While it has long been recognized that bi-directional interaction between the heart and the
vasculature plays a critical role in the proper functioning of the cardiovascular system, a …

Objective Although the aortic interposition bypass model has been widely used to evaluate
biomaterials for bypass grafting, there is no comprehensive description of the procedure or …

Objectives The loss or damage of an organ or tissue is one of the most common and
devastating problems in healthcare today. Tissue engineering applies the principles of …

Peripheral arterial disease causes blood vessel dysfunction that requires surgical
intervention. Current surgical interventions employ synthetic or allogeneic vascular grafts …

Background In elastic and resistance arteries, an elastin-rich membrane, the Internal Elastic
Lamina (IEL), separates the tunica intima from the underlying tunica media. The IEL often …

Background Atherosclerosis occurs as a result of low-density lipoprotein (LDL) deposits
oxidation. Endothelial dysfunction is an early process of atherosclerosis. Restoring …

Tunica adventitia was previously considered an inert fibrous layer only involved in nutritional
and physical support of the arterial wall. Recent studies reveal that it is an important dynamic …

The purpose of this study was to evaluate the diameter and thickness-related variations in
mechanical properties of degraded arterial wall. To this end, ring tests were performed on 31 …

Regional differences in the aortic wall are important in explaining the physicomechanical
properties and disease distribution in this artery. The goat is a suitable model for studying …

Light microscopy analysis of the mural structure of the common carotid artery, internal
carotid artery and external carotid artery in mongrel dog revealed variability in the middle …