The sequencing of chromosome 21 and the use of models of Down's syndrome in mice have
allowed us to relate genes and sets of genes to the neuropathogenesis of this syndrome …

Rich with the voices and stories of participants, these touching, firsthand accounts examine
how women of diverse racial, ethnic, class and religious backgrounds perceive prenatal …

Routine prenatal screening is based on the assumption that it is reasonable for prospective
parents to choose to prevent a life with Down's syndrome. This paper questions whether …

Background Stigmatization is one of the greatest obstacles to the successful integration of
people with Trisomy 21 (T21 or Down syndrome), the most frequent genetic disorder …

This article reviews the literature on prenatal screening for Down's syndrome. To be
evidence based, medicine and nursing have to take account of research evidence and also …

The purpose of this analysis was to assess the applicability of the Family Management
Measure (FaMM) to families in which there was a child with an intellectual disability versus a …

Objective To study the attitudes of pregnant women towards termination of pregnancy for
fetal abnormality. Materials and methods A questionnaire was completed by all pregnant …

Purpose This study aimed to determine Down syndrome (DS) burden using years lived with
disability (YLDs), years of life lost (YLLs), disability-adjusted life years (DALYs), and the …

Objective To investigate the attitudes towards termination of pregnancy (TOP) among Hong
Kong Chinese women attending the prenatal diagnosis counselling (PDC) clinic under three …

Este estudo teve como objetivo comparar as condições emocionais de mães cujos filhos
nascem com malformações visíveis, em dois momentos: após o nascimento e três meses …