Arterial stiffness progressively increases with aging and is an independent predictor of
cardiovascular disease (CVD) risk. Evidence supports that there are sex differences in the …

Prevention of cardiovascular disease (CVD) remains one of the largest public health
challenges of our time. Identifying individuals at increased cardiovascular risk at an …

Cardiovascular diseases (CVD) remain the leading cause of morbidity and mortality in both
men and women in developed societies. Age is the greatest risk factor for CVD due largely …

Increasing evidence indicates that physical activity and exercise training may delay or
prevent the onset of Alzheimer's disease (AD). However, systemic biomarkers that can …

Aims It is unknown whether different training modalities exert differential cellular effects.
Telomeres and telomere-associated proteins play a major role in cellular aging with …

Age-associated cardiovascular (CV) dysfunction, namely arterial dysfunction, is a key
antecedent to the development of CV disease (CVD). Arterial dysfunction with aging is …

The year 2017 marked the 20th anniversary of the first publication describing Klotho. This
single protein was and is remarkable in that its absence in mice conferred an accelerated …

Epidemiological studies have shown that ageing is a major non-reversible risk factor for
cardiovascular disease. Vascular ageing starts early in life and is characterized by a gradual …

Vascular aging, featuring endothelial dysfunction and large artery stiffening, is a major risk
factor for developing cardiovascular disease (CVD). In women, vascular aging appears to be …

Vascular aging, featuring endothelial dysfunction and large elastic artery stiffening, is a
major risk factor for the development of age-associated cardiovascular diseases (CVDs) …