Remodeled tumor immune microenvironment (TIME) parade via natural killer cells reprogramming in breast cancer

MM Elanany, D Mostafa, NM Hamdy - Life sciences, 2023 - Elsevier
Breast cancer (BC) is the main cause of cancer-related mortality among women globally.
Despite substantial advances in the identification and management of primary tumors …

Phosphorous dendron micelles as a nanomedicine platform for cooperative tumor chemoimmunotherapy via synergistic modulation of immune cells

M Zhan, J Qiu, Y Fan, L Chen, Y Guo… - Advanced …, 2023 - Wiley Online Library
Abstract Design of effective nanomedicines to modulate multiple immune cells to overcome
the immune‐suppressive tumor microenvironment is desirable to improve the overall poor …

Advances in natural killer cell therapies for breast cancer

SZF Kiaei, A Nouralishahi… - … and Cell Biology, 2023 - Wiley Online Library
Breast cancer (BC) is the most common cause of cancer death in women. According to the
American Cancer Society's yearly cancer statistics, BC constituted almost 15% of all the …

Tumor organoid and spheroid models for cervical cancer

I Kutle, R Polten, J Hachenberg, R Klapdor, M Morgan… - Cancers, 2023 - mdpi.com
Simple Summary Appropriate testing models are imperative to facilitate the discovery of
effective personalized treatments against different cancers, including advanced cervical …

[HTML][HTML] Immunomodulatory activity of the tyrosine kinase inhibitor dasatinib to elicit NK cytotoxicity against cancer, HIV infection and aging

A Rodríguez-Agustín, V Casanova, J Grau-Expósito… - Pharmaceutics, 2023 - mdpi.com
Tyrosine kinase inhibitors (TKIs) have been extensively used as a treatment for chronic
myeloid leukemia (CML). Dasatinib is a broad-spectrum TKI with off-target effects that give it …

Impact of doxorubicin-loaded ferritin nanocages (FerOX) vs. free doxorubicin on T lymphocytes: a translational clinical study on breast cancer patients undergoing …

M Sevieri, F Andreata, F Mainini, L Signati… - Journal of …, 2024 - Springer
Despite the advent of numerous targeted therapies in clinical practice, anthracyclines,
including doxorubicin (DOX), continue to play a pivotal role in breast cancer (BC) treatment …

Display of Polyvalent Hybrid Antibodies on the Cell Surface for Enhanced Cell Recognition

X Wang, Y Wang, K Lee, B Davis, C Wen, B Jia… - Small …, 2024 - Wiley Online Library
Cell surface engineering with exogeneous receptors holds great promise for various
applications. However, current biological methods face problems with safety, antigen …

Decoding cell death signalling: Impact on the response of breast cancer cells to approved therapies

L Lozon, WS Ramadan, RR Kawaf, AM Al-Shihabi… - Life Sciences, 2024 - Elsevier
Breast cancer is a principal cause of cancer-related mortality in female worldwide. While
many approved therapies have shown promising outcomes in treating breast cancer …

Genistein sensitizes human cholangiocarcinoma cell lines to be susceptible to natural killer cells

C Chiawpanit, S Panwong, N Sawasdee… - Biology, 2022 - mdpi.com
Simple Summary Cholangiocarcinoma (CCA) is a malignancy of bile duct epithelial cells,
which has a poor prognosis and high mortality. Consequently, effective therapeutic options …

Application of nanoparticles in breast cancer treatment: a systematic review

S Bourang, M Noruzpour… - Naunyn-Schmiedeberg's …, 2024 - Springer
It is estimated that cancer is the second leading cause of death worldwide. The primary or
secondary cause of cancer-related mortality for women is breast cancer. The main treatment …