Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …

Cardiovascular disease, a leading cause of mortality worldwide, is caused mainly by
atherosclerosis, a chronic inflammatory disease of blood vessels. Lesions of atherosclerosis …

At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Oxidation reactions are vital parts of metabolism and signal transduction. However, they also
produce reactive oxygen species, which damage lipids, proteins and DNA, generating …

Pulmonary arterial hypertension (PAH) is characterized by enhanced proliferation and
reduced apoptosis of pulmonary artery smooth muscle cells (PASMCs). Because …

Glycerophospholipids represent a common class of lipids critically important for integrity of
cellular membranes. Oxidation of esterified unsaturated fatty acids dramatically changes …

Atherosclerosis is an inflammatory vascular disease responsible for the first cause of
mortality worldwide. Recent studies have clearly highlighted the critical role of the …

STAT3 is constitutively activated in colon cancer but its contributions in cancer-initiating cells
have not been explored. In this study, we characterized STAT3 in aldehyde dehydrogenase …

Objective—Hyperlipidemia-induced endothelial cell (EC) activation is considered as an
initial event responsible for monocyte recruitment in atherogenesis. However, it remains …

Background The nature and underlying mechanisms of an inverse association between
adult height and the risk of coronary artery disease (CAD) are unclear. Methods We used a …