Enhancement of clinical signs in C3H/HeJ mice vaccinated with a highly immunogenic Leptospira methyl-accepting chemotaxis protein following challenge

LN Barbosa, A LIanes, S Madesh… - PLOS Neglected …, 2024 - journals.plos.org
Leptospirosis is the most widespread zoonosis and a life-threatening disease in humans
and animals. Licensed killed whole-cell vaccines are available for animals; however, they …

[HTML][HTML] Development of a novel multi-epitope vaccine candidate against Streptococcus iniae infection in fish: an immunoinformatics study

A Forouharmehr, A Banan, A Jaydari - Archives of Razi Institute, 2022 - ncbi.nlm.nih.gov
Streptococcus Iniae infection is recognized as a disease with substantial economic losses,
infecting a wide range of fish species. The limitations of current vaccines and strategies have …

Designing an efficient epitope-based vaccine conjugated with a molecular adjuvant against Bovine Babesiosis: A computational study

A Forouharmehr, N Nazifi, SM Mousavi, A Jaydari - Process Biochemistry, 2022 - Elsevier
The current study was designed to introduce an efficient epitope-based vaccine against
bovine babesiosis. Four immunogenic proteins of the Babesia. bovis including Trap, msa …

Determination of immunodominant scaffolds of Com1 and OmpH antigens of Coxiella burnetii

A Jaydari, A Forouharmehr, N Nazifi - Microbial pathogenesis, 2019 - Elsevier
Today, there is an increasing emphasis on recombinant vaccines to eliminate the side
effects of conventional vaccines such as whole-cell bacteria. Query fever is an emerging …

Recent progress in the treatment of leptospirosis

C Gopi, CS Sri, G Krupamai, AR Magesh… - SN Comprehensive …, 2021 - Springer
Leptospirosis is an acute anthropozoonotic infection that affects humans and animals in the
last few decades due to being seriously neglected by countries located in a temperate …

Engineering an efficient poly-epitope vaccine against Toxoplasma gondii infection: a computational vaccinology study

A Forouharmehr - Microbial Pathogenesis, 2021 - Elsevier
Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. Despite the importance
of toxoplasmosis, there is no comprehensive strategy to control this disease. Hence …

Immunoinformatics Approach to Engineer a Potent Poly-epitope Fusion Protein Vaccine Against Coxiella burnetii

E Rashidian, ZS Gandabeh, A Forouharmehr… - International Journal of …, 2020 - Springer
Coxiella burnetii pathogen, which causes Q fever, is one of the most dangerous pathogens
transmitted from the livestock to humans. The only immunization against this disease is the …

In silico analysis of epitope-based CadF vaccine design against Campylobacter jejuni

M Moballegh Naseri, S Shams, M Moballegh Naseri… - BMC Research …, 2020 - Springer
Objective Vaccination is an important strategy for the eradication of infectious diseases.
CadF protein of Campylobacter jejuni is one of the important factors in the pathogenesis of …

[HTML][HTML] Production and characterization of immunoglobulin G anti-rLipL32 antibody as a biomarker for the diagnosis of leptospirosis

S Susanti, PP Sudarmono, NLPI Dharmayanti… - Veterinary …, 2024 - ncbi.nlm.nih.gov
Materials and Methods: Escherichia coli rLipL32 was cultured and analyzed by PCR and
sequencing. Cultures were used for rLipL32 protein expression and purification and the …

[HTML][HTML] Introduction of a novel poly-epitope vaccine against mycobacterium tuberculosis infection; an immunoinformatics approach

E Rashidian, A Forouharmehr… - International Journal of …, 2021 - brieflands.com
Background: Tuberculosis is known as one of the most dangerous diseases caused by
Mycobacterium tuberculosis. Although different strategies have been applied to prevent this …