Plasma cell neoplasms and related entities—evolution in diagnosis and classification
F Fend, A Dogan, JR Cook - Virchows Archiv, 2023 - Springer
Plasma cell neoplasms including multiple myeloma (MM) and related terminally
differentiated B-cell neoplasms are characterized by secretion of monoclonal …
differentiated B-cell neoplasms are characterized by secretion of monoclonal …
Advances in the molecular characterization of multiple myeloma and mechanism of therapeutic resistance
M Mejia Saldarriaga, W Darwiche, D Jayabalan… - Frontiers in …, 2022 - frontiersin.org
Recent insight in the genomic landscape of newly diagnosed multiple myeloma (NDMM)
and its precursor conditions, monoclonal gammopathy of uncertain significance (MGUS) …
and its precursor conditions, monoclonal gammopathy of uncertain significance (MGUS) …
Plasma cell–derived mtDAMPs activate the macrophage STING pathway, promoting myeloma progression
A Jibril, C Hellmich, EE Wojtowicz… - Blood, The Journal …, 2023 - ashpublications.org
Mitochondrial damage–associated molecular patterns (mtDAMPs) include proteins, lipids,
metabolites, and DNA and have various context-specific immunoregulatory functions. Cell …
metabolites, and DNA and have various context-specific immunoregulatory functions. Cell …
Diagnosis and management of smouldering myeloma: a British Society for Haematology Good Practice Paper
Multiple myeloma (MM) is a clonal bone marrow disorder of plasma cells. MM is preceded
by the precursor conditions monoclonal gammopathy of undetermined significance (MGUS) …
by the precursor conditions monoclonal gammopathy of undetermined significance (MGUS) …
Real-world characteristics and outcomes of patients with high-risk and non-high-risk smoldering multiple myeloma using the Flatiron Health database
SV Rajkumar, MV Mateos, M Schaeffer, X Lin… - Blood Cancer …, 2024 - nature.com
This study aimed to provide real-world evidence on progression risk in patients with high-
risk smoldering multiple myeloma (SMM). This retrospective, observational study leveraged …
risk smoldering multiple myeloma (SMM). This retrospective, observational study leveraged …
Comprehensive analysis of prognosis of cuproptosis-related oxidative stress genes in multiple myeloma
T Li, L Yao, Y Hua, Q Wu - Frontiers in Genetics, 2023 - frontiersin.org
Introduction: Multiple myeloma (MM) is a highly heterogeneous hematologic malignancy.
The patients' survival outcomes vary widely. Establishing a more accurate prognostic model …
The patients' survival outcomes vary widely. Establishing a more accurate prognostic model …
Gene interaction network analysis in multiple myeloma detects complex immune dysregulation associated with shorter survival
The plasma cell cancer multiple myeloma (MM) varies significantly in genomic
characteristics, response to therapy, and long-term prognosis. To investigate global …
characteristics, response to therapy, and long-term prognosis. To investigate global …
Inference of genomic lesions from single-cell RNA-seq in myeloma improves functional intraclonal and interclonal analysis
F Lazzaroni, A Matera, A Marella, A Maeda… - Blood …, 2024 - ashpublications.org
Smoldering multiple myeloma (SMM) is an asymptomatic plasma cell (PC) neoplasm that
may evolve with variable frequency into multiple myeloma (MM). SMM is initiated by …
may evolve with variable frequency into multiple myeloma (MM). SMM is initiated by …
Waldenström macroglobulinemia whole genome reveals prolonged germinal center activity and late copy number aberrations
KH Maclachlan, T Bagratuni, E Kastritis… - Blood …, 2023 - ashpublications.org
The genomic landscape of Waldenström macroglobulinemia (WM) is characterized by
somatic mutations in MYD88, present from the precursor stages. Using the comprehensive …
somatic mutations in MYD88, present from the precursor stages. Using the comprehensive …
Smoldering multiple myeloma: taking the narrow over the wide path?
H Avet-Loiseau, NJ Bahlis - Blood, 2024 - ashpublications.org
Smoldering multiple myeloma (MM) is an asymptomatic clonal plasma cell condition
considered as a premalignant entity that may evolve over time to symptomatic MM. Based on …
considered as a premalignant entity that may evolve over time to symptomatic MM. Based on …