This review article will consider the preparation and application of ynones in synthetic
organic chemistry. Concerning the preparation of these bifunctional compounds, several …

Chalcogen bonding (ChB) has emerged as a promising tool in organic synthesis. However,
compared with the well‐developed selenium‐and tellurium‐based salt catalysts, the ChB …

The review summarizes data on natural compounds including higher carboxylic acids,
acetogenins, lembehynes, and insect pheromones containing bis-methylene-interrupted Z …

Herein, we report a Pd‐catalyzed enantioselective domino Heck carbonylation reaction of o‐
iodoacrylanilides with terminal alkynes and water as the nucleophiles, affording a diversity …

A series of 25 chiral anti-cancer lipidic alkynylcarbinols (LACs) were devised by introducing
an (hetero) aromatic ring between the aliphatic chain and the dialkynylcarbinol warhead …

A series of new chiral aminophenol sulfonamide ligands with a monochiral arm has been
developed for the first Cu (I) catalyzed enantiodivergent alkynylation of isatins. Dramatic …

The stereoselective synthesis of (5 Z, 9 Z)-tetradeca-5, 9-diene-1, 14-diol was carried out by
the catalytic homo-cyclomagnesiation of oxygen-containing 1, 2-diene. Selective syntheses …

The first Z-stereoselective method for the synthesis of the natural marine alkynol lembehyne
C, containing a 1 Z, 5 Z, 9 Z-triene moiety, in 41% yield was developed using the new Ti …

A copper-catalyzed enantioselective alkynylation between terminal alkynes and pyrazole-4,
5-diones has been developed. With 2.5 mol% CuI and 3 mol% chiral ligand L15, chiral …

Ynones are efficiently reduced with a mild hydride donor in the presence of a catalytic
amount of nucleophilic phosphines. The reactions are selective 1, 2-reductions that give …