Since 1997, bispectral index (BIS; Aspect Medical Systems Inc., Natick, MA) has been in
clinical practice and a wealth of experimental research has accumulated on its use …

Purpose Sedatives administered to critically ill children should be titrated to effect, because
both under-and oversedation may have negative effects. We conducted a systematic review …

Objectives: To examine pediatric intensivist sedation management, sleep promotion, and
delirium screening practices for intubated and mechanically ventilated children. Design: An …

IMPLICATIONS: The Bispectral Index monitor is a quantitative, easy to use method of
assessing the depth of sedation in children that, unlike clinical sedation assessing methods …

Abstract Background. Entropy and Bispectral Index™(BIS™) have been promoted as EEG-
based anaesthesia depth monitors. The EEG changes with brain maturation, but there are …

Background Current recommended discharge criteria might not be rigorous enough to
detect residual sedation. This study evaluated the use of the Bispectral Index (BIS monitor) …

Background Bispectral index (BIS) and entropy monitors have been proposed for use in
children, but research has not supported their validity for infants. However, effective …

We performed this study to compare the correlation of bispectral index (BIS) values with
different sevoflurane concentrations between normal children and those with quadriplegic …

Background: Bispectral index (BIS) is a signal processing device that potentially is a
pharmacodynamic measure of the effects of anaesthesia on the central nervous system …

Background. The bispectral index (BIS) has been evaluated as a tool for measuring depth of
anaesthesia, but the use of BIS in a paediatric population is still controversial. This study …