Surgical and tissue engineering strategies for articular cartilage and meniscus repair

H Kwon, WE Brown, CA Lee, D Wang… - Nature Reviews …, 2019 - nature.com
Injuries to articular cartilage and menisci can lead to cartilage degeneration that ultimately
results in arthritis. Different forms of arthritis affect~ 50 million people in the USA alone, and it …

[HTML][HTML] Cartilage integrity: A review of mechanical and frictional properties and repair approaches in osteoarthritis

P Krakowski, A Rejniak, J Sobczyk, R Karpiński - Healthcare, 2024 - mdpi.com
Osteoarthritis (OA) is one of the most common causes of disability around the globe,
especially in aging populations. The main symptoms of OA are pain and loss of motion and …

Autologous chondrocyte implantation in the knee: systematic review and economic evaluation

H Mistry, M Connock, J Pink… - Health Technology …, 2017 - wrap.warwick.ac.uk
Background: The surfaces of the bones in the knee are covered with articular cartilage, a
rubber-like substance that is very smooth, allowing frictionless movement in the joint and …

[HTML][HTML] An educational review of cartilage repair: precepts & practice–myths & misconceptions–progress & prospects

EB Hunziker, K Lippuner, MJB Keel… - Osteoarthritis and …, 2015 - Elsevier
Objective The repair of cartilaginous lesions within synovial joints is still an unresolved and
weighty clinical problem. Although research activity in this area has been indefatigably …

Management of articular cartilage defects of the knee

A Bedi, BT Feeley, RJ Williams III - JBJS, 2010 - journals.lww.com
Management of Articular Cartilage Defects of the Knee : JBJS Management of Articular
Cartilage Defects of the Knee : JBJS JBJS Journal Case Connector Reviews JBJS.org Surgical …

A systematic review and guide to mechanical testing for articular cartilage tissue engineering

JM Patel, BC Wise, ED Bonnevie… - Tissue Engineering Part …, 2019 - liebertpub.com
Articular cartilage is integral to the mechanical function of many joints in the body. When
injured, cartilage lacks the capacity to self-heal, and thus, therapies and replacements have …

Outcomes after a single-stage procedure for cell-based cartilage repair: a prospective clinical safety trial with 2-year follow-up

BJ Cole, J Farr, CS Winalski, T Hosea… - … American Journal of …, 2011 - journals.sagepub.com
Background: There are currently several approaches being pursued to treat focal defects of
articular cartilage, each having specific advantages or challenges. A single-stage procedure …

[HTML][HTML] Increased recruitment of endogenous stem cells and chondrogenic differentiation by a composite scaffold containing bone marrow homing peptide for …

J Lu, X Shen, X Sun, H Yin, S Yang, C Lu, Y Wang… - Theranostics, 2018 - ncbi.nlm.nih.gov
Even small cartilage defects could finally degenerate to osteoarthritis if left untreated, owing
to the poor self-healing ability of articular cartilage. Stem cell transplantation has been well …

Emerging therapies for cartilage regeneration in currently excluded 'red knee'populations

AR Martín, JM Patel, HM Zlotnick, JL Carey… - NPJ Regenerative …, 2019 - nature.com
The field of articular cartilage repair has made significant advances in recent decades; yet
current therapies are generally not evaluated or tested, at the time of pivotal trial, in patients …

Surgical management of articular cartilage defects of the knee

AH Gomoll, J Farr, SD Gillogly, J Kercher, T Minas - JBJS, 2010 - journals.lww.com
Surgical Management of Articular Cartilage Defects of the Kn... : JBJS Surgical Management of
Articular Cartilage Defects of the Knee : JBJS JBJS Journal Case Connector Reviews JBJS.org …