Dispositional negativity, cognition, and anxiety disorders: An integrative translational neuroscience framework

J Hur, MD Stockbridge, AS Fox, AJ Shackman - Progress in brain research, 2019 - Elsevier
When extreme, anxiety can become debilitating. Anxiety disorders, which often first emerge
early in development, are common and challenging to treat, yet the underlying mechanisms …

[HTML][HTML] Greater decision uncertainty characterizes a transdiagnostic patient sample during approach-avoidance conflict: a computational modelling approach

R Smith, N Kirlic, JL Stewart, J Touthang… - Journal of Psychiatry and …, 2021 - jpn.ca
Background Imbalances in approach-avoidance conflict (AAC) decision-making (eg,
sacrificing rewards to avoid negative outcomes) are considered central to multiple …

[HTML][HTML] Increased pain sensitivity and pain-related anxiety in individuals with autism

MD Failla, MB Gerdes, ZJ Williams, DJ Moore… - Pain …, 2020 - journals.lww.com
Objectives: We hypothesized that individuals with ASD would report increased pain
sensitivity and endorse more pain-related anxiety, compared to typically developing …

Adolescent alcohol exposure produces sex differences in negative affect-like behavior and group I mGluR BNST plasticity

CR Kasten, KL Carzoli, NM Sharfman… - …, 2020 - nature.com
Adolescent alcohol exposure increases the risk of developing alcohol use disorders (AUDs),
yet the mechanisms responsible for this vulnerability remain largely unknown. One potential …

[HTML][HTML] Metabotropic glutamate receptor subtype 5 in alcohol-induced negative affect

CR Kasten, EB Holmgren, TA Wills - Brain Sciences, 2019 - mdpi.com
Allosteric modulators of metabotropic glutamate 5 receptors (mGlu5 receptors) have been
identified as a promising treatment to independently alleviate both negative affective states …

[HTML][HTML] Neurofeedback-augmented mindfulness training elicits distinct responses in the subregions of the insular cortex in healthy adolescents

X Yu, ZP Cohen, A Tsuchiyagaito, G Cochran… - Brain Sciences, 2022 - mdpi.com
Mindfulness training (MT) reduces self-referential processing and promotes interoception,
the perception of sensations from inside the body, by increasing one's awareness of and …

[HTML][HTML] BNST specific mGlu5 receptor knockdown regulates sex-dependent expression of negative affect produced by adolescent ethanol exposure and adult stress

CR Kasten, EB Holmgren, MR Lerner… - Translational Psychiatry, 2021 - nature.com
Adolescent alcohol use is one of the strongest predictors for the development of an alcohol
use disorder (AUD). Notably, this period of risk coincides with the development of affective …

[HTML][HTML] Abnormal functional connectivity in psoriasis patients with depression is associated with their clinical symptoms

X Wang, N Liu, L Wu, Y Zhang, G Zhang - Frontiers in Neuroscience, 2022 - frontiersin.org
Psoriasis is a chronic, autoimmune disorder that is related to mental health disorders such
as depression. However, few studies have focused on the features of brain activity in …

Aversive perception in a threat context: Separate and independent neural activation

N Sambuco, VD Costa, PJ Lang, MM Bradley - Biological psychology, 2020 - Elsevier
Unpleasant, compared to neutral, scenes reliably prompt enhanced functional brain activity
in the amygdala and inferotemporal cortex. Considering data from psychophysiological …

[HTML][HTML] Emotional memory and amygdala activation

MM Bradley, N Sambuco - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
Determining the neural correlates of emotional memory is critical for understanding both
healthy and psychopathological emotional processing, and meta-analyses summarizing …