Dispositional negativity, cognition, and anxiety disorders: An integrative translational neuroscience framework
When extreme, anxiety can become debilitating. Anxiety disorders, which often first emerge
early in development, are common and challenging to treat, yet the underlying mechanisms …
early in development, are common and challenging to treat, yet the underlying mechanisms …
[HTML][HTML] Greater decision uncertainty characterizes a transdiagnostic patient sample during approach-avoidance conflict: a computational modelling approach
Background Imbalances in approach-avoidance conflict (AAC) decision-making (eg,
sacrificing rewards to avoid negative outcomes) are considered central to multiple …
sacrificing rewards to avoid negative outcomes) are considered central to multiple …
[HTML][HTML] Increased pain sensitivity and pain-related anxiety in individuals with autism
Objectives: We hypothesized that individuals with ASD would report increased pain
sensitivity and endorse more pain-related anxiety, compared to typically developing …
sensitivity and endorse more pain-related anxiety, compared to typically developing …
Adolescent alcohol exposure produces sex differences in negative affect-like behavior and group I mGluR BNST plasticity
CR Kasten, KL Carzoli, NM Sharfman… - …, 2020 - nature.com
Adolescent alcohol exposure increases the risk of developing alcohol use disorders (AUDs),
yet the mechanisms responsible for this vulnerability remain largely unknown. One potential …
yet the mechanisms responsible for this vulnerability remain largely unknown. One potential …
[HTML][HTML] Metabotropic glutamate receptor subtype 5 in alcohol-induced negative affect
Allosteric modulators of metabotropic glutamate 5 receptors (mGlu5 receptors) have been
identified as a promising treatment to independently alleviate both negative affective states …
identified as a promising treatment to independently alleviate both negative affective states …
[HTML][HTML] Neurofeedback-augmented mindfulness training elicits distinct responses in the subregions of the insular cortex in healthy adolescents
Mindfulness training (MT) reduces self-referential processing and promotes interoception,
the perception of sensations from inside the body, by increasing one's awareness of and …
the perception of sensations from inside the body, by increasing one's awareness of and …
[HTML][HTML] BNST specific mGlu5 receptor knockdown regulates sex-dependent expression of negative affect produced by adolescent ethanol exposure and adult stress
CR Kasten, EB Holmgren, MR Lerner… - Translational Psychiatry, 2021 - nature.com
Adolescent alcohol use is one of the strongest predictors for the development of an alcohol
use disorder (AUD). Notably, this period of risk coincides with the development of affective …
use disorder (AUD). Notably, this period of risk coincides with the development of affective …
[HTML][HTML] Abnormal functional connectivity in psoriasis patients with depression is associated with their clinical symptoms
X Wang, N Liu, L Wu, Y Zhang, G Zhang - Frontiers in Neuroscience, 2022 - frontiersin.org
Psoriasis is a chronic, autoimmune disorder that is related to mental health disorders such
as depression. However, few studies have focused on the features of brain activity in …
as depression. However, few studies have focused on the features of brain activity in …
Aversive perception in a threat context: Separate and independent neural activation
Unpleasant, compared to neutral, scenes reliably prompt enhanced functional brain activity
in the amygdala and inferotemporal cortex. Considering data from psychophysiological …
in the amygdala and inferotemporal cortex. Considering data from psychophysiological …
[HTML][HTML] Emotional memory and amygdala activation
MM Bradley, N Sambuco - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
Determining the neural correlates of emotional memory is critical for understanding both
healthy and psychopathological emotional processing, and meta-analyses summarizing …
healthy and psychopathological emotional processing, and meta-analyses summarizing …