[HTML][HTML] Biological activities underlying the therapeutic effect of quercetin on inflammatory bowel disease

YL Lyu, HF Zhou, J Yang, FX Wang, F Sun… - Mediators of …, 2022 - hindawi.com
Inflammatory bowel disease (IBD) is a chronic autoimmune disorder stemming from
unrestrained immune activation and subsequent destruction of colon tissue. Genetic …

[HTML][HTML] Inflammatory auto-immune diseases of the intestine and their management by natural bioactive compounds

N El Menyiy, A El Allam, S Aboulaghras… - Biomedicine & …, 2022 - Elsevier
Autoimmune diseases are caused by the overactivity of the immune system towards self-
constituents. Risk factors of autoimmune diseases are multiple and include genetic …

pH/ROS dual-sensitive natural polysaccharide nanoparticles enhance “one stone four birds” effect of rhein on ulcerative colitis

S Qi, R Luo, X Han, W Nie, N Ye, C Fu… - ACS Applied Materials & …, 2022 - ACS Publications
Rhein (RH), a natural anthraquinone compound, is considered an effective treatment
candidate for ulcerative colitis (UC), whose multiple biological activities contribute to UC …

Surfactin mitigates dextran sodium sulfate-induced colitis and behavioral disorders in mice by mediating gut–brain-axis balance

X Chen, H Zhao, Y Lu, F Meng, Z Lu… - Journal of Agricultural …, 2023 - ACS Publications
Ulcerative colitis (UC) is associated with brain neurotransmitter disorders and intestinal
dysbiosis. Bacillus amyloliquefaciens fmb50 produces the lipopeptide surfactin, which has a …

[HTML][HTML] Natural products targeting Nrf2/ARE signaling pathway in the treatment of inflammatory bowel disease

B Li, Y Wang, X Jiang, H Du, Y Shi, M Xiu, Y Liu… - Biomedicine & …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a special chronic intestinal inflammatory disease, which
is mainly divided into Crohn's disease (CD) and ulcerative colitis (UC). Its occurrence is a …

Oral pectin/oligochitosan microspheres for colon-specific controlled release of quercetin to treat inflammatory bowel disease

S Jing, H Chen, E Liu, M Zhang, F Zeng, H Shen… - Carbohydrate …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a chronic, life quality-reducing disease with no cures
available yet. To develop an effective medication suitable for long-term use is an urgent but …

Folic acid-modified lactoferrin nanoparticles coated with a laminarin layer loaded curcumin with dual-targeting for ulcerative colitis treatment

N Ye, P Zhao, S Ayue, S Qi, Y Ye, H He, L Dai… - International Journal of …, 2023 - Elsevier
Curcumin (CUR) is a promising natural compound in ulcerative colitis (UC) treatment, but
limited by its low oral bioavailability and poor targeting ability. Therefore, given the targeting …

Alginate-based drug carrier systems to target inflammatory bowel disease: A review

D Swastha, N Varsha, S Aravind, KB Samyuktha… - International Journal of …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is an inflammatory disorder that affects the gastrointestinal
tract. IBD has become an increasingly common condition in both developed and developing …

Anti-Inflammatory and Antioxidant Effects Induced by Allium sativum L. Extracts on an Ex Vivo Experimental Model of Ulcerative Colitis

L Recinella, E Gorica, A Chiavaroli, C Fraschetti… - Foods, 2022 - mdpi.com
Inflammatory bowel diseases (IBDs) are chronic and multifactorial inflammatory conditions of
the colonic mucosa (ulcerative colitis), characterized by increased and unbalanced immune …

[HTML][HTML] Limonin, a natural ERK2 agonist, protects against ischemic acute kidney injury

X Zhou, Y Xiang, D Li, M Zhong, X Hong… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is a refractory clinical syndrome with limited effective treatments.
Amid AKI, activation of the extracellular signal-regulated kinase (ERK) cascade plays a …