Evolution of SARS-CoV-2 variants: implications on immune escape, vaccination, therapeutic and diagnostic strategies

NZ Zabidi, HL Liew, IA Farouk, A Puniyamurti, AJW Yip… - Viruses, 2023 - mdpi.com
The COVID-19 pandemic caused by SARS-CoV-2 is associated with a lower fatality rate
than its SARS and MERS counterparts. However, the rapid evolution of SARS-CoV-2 has …

[HTML][HTML] Delivery of biologics: Topical administration

RJ Kulchar, R Singh, S Ding, E Alexander, KW Leong… - Biomaterials, 2023 - Elsevier
Biologics are unaffordable to a large majority of the global population because of
prohibitively expensive fermentation systems, purification and the requirement for cold chain …

The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

H Tegally, JE San, M Cotten, M Moir, B Tegomoh… - Science, 2022 - science.org
Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing
in Africa over the past year has led to a major increase in the number of sequences that …

Targeted accurate RNA consensus sequencing (tARC-seq) reveals mechanisms of replication error affecting SARS-CoV-2 divergence

CC Bradley, C Wang, AJE Gordon, AX Wen… - Nature …, 2024 - nature.com
RNA viruses, like SARS-CoV-2, depend on their RNA-dependent RNA polymerases (RdRp)
for replication, which is error prone. Monitoring replication errors is crucial for understanding …

SARS-CoV-2 variants identification: overview of molecular existing methods

G Berno, L Fabeni, G Matusali, CEM Gruber, M Rueca… - Pathogens, 2022 - mdpi.com
Since the beginning of COVID-19 pandemic the Real Time sharing of genome sequences of
circulating virus supported the diagnostics and surveillance of SARS-CoV-2 and its …

The effects of amino acid substitution of spike protein and genomic recombination on the evolution of SARS-CoV-2

L Fang, J Xu, Y Zhao, J Fan, J Shen, W Liu… - Frontiers in …, 2023 - frontiersin.org
Over three years' pandemic of 2019 novel coronavirus disease (COVID-19), multiple
variants and novel subvariants have emerged successively, outcompeted earlier variants …

High-resolution epidemiological landscape from~ 290,000 SARS-CoV-2 genomes from Denmark

MP Khurana, J Curran-Sebastian… - Nature …, 2024 - nature.com
Vast amounts of pathogen genomic, demographic and spatial data are transforming our
understanding of SARS-CoV-2 emergence and spread. We examined the drivers of …

Evolutionary dynamics of dengue virus in India

S Jagtap, C Pattabiraman, A Sankaradoss… - PLoS …, 2023 - journals.plos.org
More than a hundred thousand dengue cases are diagnosed in India annually, and about
half of the country's population carries dengue virus-specific antibodies. Dengue propagates …

Comparison of genome replication fidelity between SARS-CoV-2 and influenza A virus in cell culture

Y Kawasaki, H Abe, J Yasuda - Scientific Reports, 2023 - nature.com
Since the emergence of COVID-19, several SARS-CoV-2 (severe acute respiratory
syndrome coronavirus 2) variants have emerged and spread widely. These variants are …

Multiplex real-time RT-PCR method for the diagnosis of SARS-CoV-2 by targeting viral N, RdRP and human RP genes

H Tombuloglu, H Sabit, H Al-Khallaf, JH Kabanja… - Scientific reports, 2022 - nature.com
Abstract Corona Virus Disease 2019 (COVID-19) is a disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). This pandemic has brought the world to …