From inflammation to fibrosis—molecular and cellular mechanisms of myocardial tissue remodelling and perspectives on differential treatment opportunities
N Suthahar, WC Meijers, HHW Silljé… - Current heart failure …, 2017 - Springer
Abstract Purpose of Review In this review, we highlight the most important cellular and
molecular mechanisms that contribute to cardiac inflammation and fibrosis. We also discuss …
molecular mechanisms that contribute to cardiac inflammation and fibrosis. We also discuss …
[HTML][HTML] Galectin-3 activation and inhibition in heart failure and cardiovascular disease: an update
Galectin-3 is a versatile protein orchestrating several physiological and pathophysiological
processes in the human body. In the last decade, considerable interest in galectin-3 has …
processes in the human body. In the last decade, considerable interest in galectin-3 has …
Left ventricular remodeling after myocardial infarction: from physiopathology to treatment
Myocardial infarction (MI) is the leading cause of death and morbidity worldwide, with an
incidence relatively high in developed countries and rapidly growing in developing …
incidence relatively high in developed countries and rapidly growing in developing …
IL (interleukin)-10–STAT3–galectin-3 axis is essential for osteopontin-producing reparative macrophage polarization after myocardial infarction
K Shirakawa, J Endo, M Kataoka, Y Katsumata… - Circulation, 2018 - Am Heart Assoc
Background: Both osteopontin (OPN) and galectin-3 have been implicated in phagocytic
clearance of dead cells and reparative fibrosis during wound healing. CD206+ …
clearance of dead cells and reparative fibrosis during wound healing. CD206+ …
Understanding cardiac extracellular matrix remodeling to develop biomarkers of myocardial infarction outcomes
SH Nielsen, AJ Mouton, KY DeLeon-Pennell… - Matrix Biology, 2019 - Elsevier
Cardiovascular Disease (CVD) is the most common cause of death in industrialized
countries, and myocardial infarction (MI) is a major CVD with significant morbidity and …
countries, and myocardial infarction (MI) is a major CVD with significant morbidity and …
[HTML][HTML] Биомаркеры острого инфаркта миокарда: диагностическая и прогностическая ценность. Часть 2 (обзор литературы)
АМ Чаулин, ДВ Дупляков - Клиническая практика, 2020 - cyberleninka.ru
Во второй части обзора мы продолжаем начатое ранее обсуждение биомаркеров,
имеющих диагностическое и прогностическое значение при остром инфаркте …
имеющих диагностическое и прогностическое значение при остром инфаркте …
The diagnostic and therapeutic potential of galectin-3 in cardiovascular diseases
G Sygitowicz, A Maciejak-Jastrzębska, D Sitkiewicz - Biomolecules, 2021 - mdpi.com
Galectin-3 plays a prominent role in chronic inflammation and has been implicated in the
development of many disease conditions, including heart disease. Galectin-3, a regulatory …
development of many disease conditions, including heart disease. Galectin-3, a regulatory …
Diagnostic and prognostic value of biomarkers in acute myocardial infarction
Y Chen, Y Tao, L Zhang, W Xu… - Postgraduate medical …, 2019 - academic.oup.com
The incidence of acute myocardial infarction (AMI) has been increasing rapidly in recent
years, seriously endangering human health. Cardiac biomarkers play critical roles in the …
years, seriously endangering human health. Cardiac biomarkers play critical roles in the …
The role of galectin-3 in heart failure—the diagnostic, prognostic and therapeutic potential—where do we stand?
B Zaborska, M Sikora-Frąc, K Smarż… - International Journal of …, 2023 - mdpi.com
Heart failure (HF) is a clinical syndrome with high morbidity and mortality, and its prevalence
is rapidly increasing. Galectin-3 (Gal-3) is an important factor in the pathophysiology of HF …
is rapidly increasing. Galectin-3 (Gal-3) is an important factor in the pathophysiology of HF …
The role of galectin‐3 in heart failure and cardiovascular disease
X Zhong, X Qian, G Chen… - Clinical and Experimental …, 2019 - Wiley Online Library
Summary Galectin‐3, a β‐galactoside‐binding lectin, is a new important player in the
progression of heart failure (HF) and is also linked to poor outcome in patients with …
progression of heart failure (HF) and is also linked to poor outcome in patients with …