Clinical management of metastatic colorectal cancer in the era of precision medicine

F Ciardiello, D Ciardiello, G Martini… - CA: a cancer journal …, 2022 - Wiley Online Library
Colorectal cancer (CRC) represents approximately 10% of all cancers and is the second
most common cause of cancer deaths. Initial clinical presentation as metastatic CRC …

[HTML][HTML] Diagnostic value of liquid biopsy in the era of precision medicine: 10 years of clinical evidence in cancer

V Caputo, F Ciardiello, CM Della Corte… - … of targeted anti-tumor …, 2023 - ncbi.nlm.nih.gov
Liquid biopsy is a diagnostic repeatable test, which in last years has emerged as a powerful
tool for profiling cancer genomes in real-time with minimal invasiveness and tailoring …

[HTML][HTML] Implementation of preventive and predictive BRCA testing in patients with breast, ovarian, pancreatic, and prostate cancer: a position paper of Italian Scientific …

A Russo, L Incorvaia, E Capoluongo, P Tagliaferri… - ESMO open, 2022 - Elsevier
Constitutional BRCA1/BRCA2 pathogenic or likely pathogenic variants (PVs) are associated
with an increased risk for developing breast and ovarian cancers. Current evidence …

[HTML][HTML] The future of precision oncology

SL Rulten, RP Grose, SA Gatz, JL Jones… - International Journal of …, 2023 - mdpi.com
Our understanding of the molecular mechanisms underlying cancer development and
evolution have evolved rapidly over recent years, and the variation from one patient to …

The tumor-agnostic treatment for patients with solid tumors: a position paper on behalf of the AIOM-SIAPEC/IAP-SIBioC-SIF Italian Scientific Societies

A Russo, L Incorvaia, U Malapelle, M Del Re… - Critical Reviews in …, 2021 - Elsevier
The personalized medicine is in a rapidly evolving scenario. The identification of actionable
mutations is revolutionizing the therapeutic landscape of tumors. The morphological and …

[HTML][HTML] Clinical potential of circulating cell-free DNA (cfDNA) for longitudinally monitoring clinical outcomes in the first-line setting of non-small-cell lung cancer …

V Gristina, N Barraco, M La Mantia, L Castellana… - Cancers, 2022 - mdpi.com
Simple Summary In the precision oncology era, liquid biopsy has dramatically revolutionized
the management of such patients, potentially overcoming tissue biopsy limitations while …

[HTML][HTML] Clinical utility of liquid biopsy-based actionable mutations detected via ddPCR

I Palacín-Aliana, N García-Romero, A Asensi-Puig… - Biomedicines, 2021 - mdpi.com
Cancer is one of the leading causes of death worldwide and remains a major public health
challenge. The introduction of more sensitive and powerful technologies has permitted the …

[HTML][HTML] Expert opinion on NSCLC small specimen biomarker testing—Part 2: Analysis, reporting, and quality assessment

F Penault-Llorca, KM Kerr, P Garrido, E Thunnissen… - Virchows Archiv, 2022 - Springer
The diagnostic work-up for non-small cell lung cancer (NSCLC) requires biomarker testing
to guide therapy choices. This article is the second of a two-part series. In Part 1, we …

The challenge of the Molecular Tumor Board empowerment in clinical oncology practice: A Position Paper on behalf of the AIOM-SIAPEC/IAP-SIBioC-SIC-SIF-SIGU …

A Russo, L Incorvaia, E Capoluongo… - Critical Reviews in …, 2022 - Elsevier
The development of innovative technologies and the advances in the genetics and
genomics, have offered new opportunities for personalized treatment in oncology. Although …

A practical guide to chimerism analysis: review of the literature and testing practices worldwide

AG Blouin, F Ye, J Williams, M Askar - Human immunology, 2021 - Elsevier
Abstract Background and Purpose Currently there are no widely accepted guidelines for
chimerism analysis testing in hematopoietic cell transplantation (HCT) patients. The …