Mesenchymal stem cells empowering tendon regenerative therapies

R Costa-Almeida, I Calejo, ME Gomes - International journal of molecular …, 2019 - mdpi.com
Tendon tissues have limited healing capacity. The incidence of tendon injuries and the
unsatisfactory functional outcomes of tendon repair are driving the search for alternative …

Achilles tendinopathy pathogenesis and management: a narrative review

D Tarantino, R Mottola, G Resta, R Gnasso… - International Journal of …, 2023 - mdpi.com
The Achilles tendon is the thickest and strongest tendon of the human body, and it is
frequently injured during sports activity. The incidence of Achilles tendon pathologies has …

Bone marrow mesenchymal stem cell-derived exosomes promote tendon regeneration by facilitating the proliferation and migration of endogenous tendon stem …

H Yu, J Cheng, W Shi, B Ren, F Zhao, Y Shi, P Yang… - Acta biomaterialia, 2020 - Elsevier
Mesenchymal stem cells (MSCs)-derived exosomes are being increasingly focused as the
new biological pro-regenerative therapeutic agents for various types of tissue injury. Here …

Electrospun thymosin Beta-4 loaded PLGA/PLA nanofiber/microfiber hybrid yarns for tendon tissue engineering application

S Wu, R Zhou, F Zhou, PN Streubel, S Chen… - Materials Science and …, 2020 - Elsevier
Microfiber yarns (MY) have been widely employed to construct tendon tissue grafts.
However, suboptimal ultrastructure and inappropriate environments for cell interactions limit …

In vitro innovation of tendon tissue engineering strategies

MR Citeroni, MC Ciardulli, V Russo… - International journal of …, 2020 - mdpi.com
Tendinopathy is the term used to refer to tendon disorders. Spontaneous adult tendon
healing results in scar tissue formation and fibrosis with suboptimal biomechanical …

Basic research on tendon repair: Strategies, evaluation, and development

ZJ Li, QQ Yang, YL Zhou - Frontiers in medicine, 2021 - frontiersin.org
Tendon is a fibro-elastic structure that links muscle and bone. Tendon injury can be divided
into two types, chronic and acute. Each type of injury or degeneration can cause substantial …

Comparison of tendon development versus tendon healing and regeneration

P He, D Ruan, Z Huang, C Wang, Y Xu… - Frontiers in Cell and …, 2022 - frontiersin.org
Tendon is a vital connective tissue in human skeletal muscle system, and tendon injury is
very common and intractable in clinic. Tendon development and repair are two closely …

Mesenchymal stem cells: An efficient cell therapy for tendon repair

L Jiang, J Lu, Y Chen, K Lyu… - International …, 2023 - spandidos-publications.com
Tendon injury is a common disorder of the musculoskeletal system caused by overuse or
trauma. With increasing incidence of tendon injuries, it is necessary to find an effective …

ADSC-based cell therapies for musculoskeletal disorders: a review of recent clinical trials

S Lee, DS Chae, BW Song, S Lim, SW Kim… - International Journal of …, 2021 - mdpi.com
Recently published clinical trials involving the use of adipose-derived stem cells (ADSCs)
indicated that approximately one-third of the studies were conducted on musculoskeletal …

Progress with stem cell therapies for tendon tissue regeneration

F Migliorini, M Tingart, N Maffulli - Expert opinion on biological …, 2020 - Taylor & Francis
Introduction Chronic musculoskeletal pain is very prevalent, and accounts for major health-
care expenses. Many of the present therapeutic modalities are only partially effective, and …