Mesenchymal stem cells empowering tendon regenerative therapies
Tendon tissues have limited healing capacity. The incidence of tendon injuries and the
unsatisfactory functional outcomes of tendon repair are driving the search for alternative …
unsatisfactory functional outcomes of tendon repair are driving the search for alternative …
Achilles tendinopathy pathogenesis and management: a narrative review
D Tarantino, R Mottola, G Resta, R Gnasso… - International Journal of …, 2023 - mdpi.com
The Achilles tendon is the thickest and strongest tendon of the human body, and it is
frequently injured during sports activity. The incidence of Achilles tendon pathologies has …
frequently injured during sports activity. The incidence of Achilles tendon pathologies has …
Bone marrow mesenchymal stem cell-derived exosomes promote tendon regeneration by facilitating the proliferation and migration of endogenous tendon stem …
H Yu, J Cheng, W Shi, B Ren, F Zhao, Y Shi, P Yang… - Acta biomaterialia, 2020 - Elsevier
Mesenchymal stem cells (MSCs)-derived exosomes are being increasingly focused as the
new biological pro-regenerative therapeutic agents for various types of tissue injury. Here …
new biological pro-regenerative therapeutic agents for various types of tissue injury. Here …
Electrospun thymosin Beta-4 loaded PLGA/PLA nanofiber/microfiber hybrid yarns for tendon tissue engineering application
S Wu, R Zhou, F Zhou, PN Streubel, S Chen… - Materials Science and …, 2020 - Elsevier
Microfiber yarns (MY) have been widely employed to construct tendon tissue grafts.
However, suboptimal ultrastructure and inappropriate environments for cell interactions limit …
However, suboptimal ultrastructure and inappropriate environments for cell interactions limit …
In vitro innovation of tendon tissue engineering strategies
MR Citeroni, MC Ciardulli, V Russo… - International journal of …, 2020 - mdpi.com
Tendinopathy is the term used to refer to tendon disorders. Spontaneous adult tendon
healing results in scar tissue formation and fibrosis with suboptimal biomechanical …
healing results in scar tissue formation and fibrosis with suboptimal biomechanical …
Basic research on tendon repair: Strategies, evaluation, and development
ZJ Li, QQ Yang, YL Zhou - Frontiers in medicine, 2021 - frontiersin.org
Tendon is a fibro-elastic structure that links muscle and bone. Tendon injury can be divided
into two types, chronic and acute. Each type of injury or degeneration can cause substantial …
into two types, chronic and acute. Each type of injury or degeneration can cause substantial …
Comparison of tendon development versus tendon healing and regeneration
P He, D Ruan, Z Huang, C Wang, Y Xu… - Frontiers in Cell and …, 2022 - frontiersin.org
Tendon is a vital connective tissue in human skeletal muscle system, and tendon injury is
very common and intractable in clinic. Tendon development and repair are two closely …
very common and intractable in clinic. Tendon development and repair are two closely …
Mesenchymal stem cells: An efficient cell therapy for tendon repair
L Jiang, J Lu, Y Chen, K Lyu… - International …, 2023 - spandidos-publications.com
Tendon injury is a common disorder of the musculoskeletal system caused by overuse or
trauma. With increasing incidence of tendon injuries, it is necessary to find an effective …
trauma. With increasing incidence of tendon injuries, it is necessary to find an effective …
ADSC-based cell therapies for musculoskeletal disorders: a review of recent clinical trials
Recently published clinical trials involving the use of adipose-derived stem cells (ADSCs)
indicated that approximately one-third of the studies were conducted on musculoskeletal …
indicated that approximately one-third of the studies were conducted on musculoskeletal …
Progress with stem cell therapies for tendon tissue regeneration
F Migliorini, M Tingart, N Maffulli - Expert opinion on biological …, 2020 - Taylor & Francis
Introduction Chronic musculoskeletal pain is very prevalent, and accounts for major health-
care expenses. Many of the present therapeutic modalities are only partially effective, and …
care expenses. Many of the present therapeutic modalities are only partially effective, and …