Modulation of the hypothalamic-pituitary-adrenal axis by early life stress exposure

M Van Bodegom, JR Homberg… - Frontiers in cellular …, 2017 - frontiersin.org
Exposure to stress during critical periods in development can have severe long-term
consequences, increasing overall risk on psychopathology. One of the key stress response …

The consequences of early‐life adversity: neurobiological, behavioural and epigenetic adaptations

S Maccari, HJ Krugers… - Journal of …, 2014 - Wiley Online Library
During the perinatal period, the brain is particularly sensitive to remodelling by
environmental factors. Adverse early‐life experiences, such as stress exposure or …

Both oxytocin and vasopressin are mediators of maternal care and aggression in rodents: from central release to sites of action

OJ Bosch, ID Neumann - Hormones and behavior, 2012 - Elsevier
In the mammalian peripartum period, the activity of both the brain oxytocin and vasopressin
system is elevated as part of the physiological adaptations occurring in the mother. This is …

The expectant brain: adapting for motherhood

PJ Brunton, JA Russell - Nature Reviews Neuroscience, 2008 - nature.com
A successful pregnancy requires multiple adaptations of the mother's physiology to optimize
fetal growth and development, to protect the fetus from adverse programming, to provide …

Effects of maternal exposure to social stress during pregnancy: consequences for mother and offspring

PJ Brunton - Reproduction, 2013 - rep.bioscientifica.com
Gonadotropins and their receptors' genes carry several single-nucleotide polymorphisms
resulting in endocrine genotypes modulating reproductive parameters, diseases, and …

Actions of prolactin in the brain: from physiological adaptations to stress and neurogenesis to psychopathology

L Torner - Frontiers in endocrinology, 2016 - frontiersin.org
Prolactin (PRL) is one of the most versatile hormones known. It is considered an adaptive
hormone due to the key roles it plays in the modulation of the stress response and during …

Prenatal social stress in the rat programmes neuroendocrine and behavioural responses to stress in the adult offspring: Sex‐specific effects

PJ Brunton, JA Russell - Journal of neuroendocrinology, 2010 - Wiley Online Library
Stress exposure during pregnancy can 'programme'adult behaviour and hypothalamic‐
pituitary‐adrenal (HPA) axis stress responsiveness. In the present study, we utilised an …

Adaptive responses of the maternal hypothalamic‐pituitary‐adrenal axis during pregnancy and lactation

PJ Brunton, JA Russell… - Journal of …, 2008 - Wiley Online Library
Over the past 40 years, it has been recognised that the maternal hypothalamic‐pituitary‐
adrenal (HPA) axis undergoes adaptations through pregnancy and lactation that might …

No stress please! Mechanisms of stress hyporesponsiveness of the maternal brain

DA Slattery, ID Neumann - The Journal of physiology, 2008 - Wiley Online Library
The time around birth is accompanied by behavioural and physiological adaptations of the
maternal brain, which ensure reproductive functions, maternal care and the survival of the …

Stress in the social context: a behavioural and eco-evolutionary perspective

KJ MacLeod, S English… - Journal of …, 2023 - journals.biologists.com
The social environment is one of the primary sources of challenging stimuli that can induce a
stress response in animals. It comprises both short-term and stable interactions among …