Reanalysis of Trichloroethylene and Tetrachloroethylene Metabolism to Glutathione Conjugates Using Human, Rat, and Mouse Liver in Vitro Models to Improve …

A Valdiviezo, GE Brown, AR Michell… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Both trichloroethylene (TCE) and tetrachloroethylene (PCE) are high-priority
chemicals subject to numerous human health risk evaluations by a range of agencies …

Ultrathin films of a metal-organic framework prepared from 2-methylimidazole, manganese (II) and cobalt (II) with strong oxidase-mimicking activity for colorimetric …

Y Zhang, C Dai, W Liu, Y Wang, F Ding, P Zou… - Microchimica Acta, 2019 - Springer
Abstract Nanosheets (NSs; type ZIF-67) of a metal organic framework (MOF) that was
prepared from 2-methylimidazole, manganese (II) and cobalt (II) were obtained by an …

Harmonization of acronyms for volatile organic compound metabolites using a standardized naming system

DS Tevis, SR Flores, BM Kenwood, D Bhandari… - International journal of …, 2021 - Elsevier
Increased interest in volatile organic compound (VOC) exposure has led to an increased
need for consistent, systematic, and informative naming of VOC metabolites. As analytical …

Metabolism and toxicity of trichloroethylene and tetrachloroethylene in cytochrome P450 2E1 knockout and humanized transgenic mice

YS Luo, S Furuya, VY Soldatov, O Kosyk… - Toxicological …, 2018 - academic.oup.com
Trichloroethylene (TCE) and tetrachloroethylene (PCE) are structurally similar olefins that
can cause liver and kidney toxicity. Adverse effects of these chemicals are associated with …

Editor's highlight: Comparative dose-response analysis of liver and kidney transcriptomic effects of trichloroethylene and tetrachloroethylene in B6C3F1 mouse

YH Zhou, JA Cichocki, VY Soldatow… - Toxicological …, 2017 - academic.oup.com
Trichloroethylene (TCE) and tetrachloroethylene (PCE) are ubiquitous environmental
contaminants and occupational health hazards. Recent health assessments of these agents …

Characterization of inter-tissue and inter-strain variability of TCE glutathione conjugation metabolites DCVG, DCVC, and NAcDCVC in the mouse

YS Luo, S Furuya, W Chiu, I Rusyn - Journal of Toxicology and …, 2018 - Taylor & Francis
Trichloroethylene (TCE) is a ubiquitous environmental toxicant that is a liver and kidney
carcinogen. Conjugation of TCE with glutathione (GSH) leads to formation of nepthrotoxic …

Using collaborative cross mouse population to fill data gaps in risk assessment: a case study of population-based analysis of toxicokinetics and kidney toxicodynamics …

YS Luo, JA Cichocki, NH Hsieh, L Lewis… - Environmental …, 2019 - ehp.niehs.nih.gov
Background: Interindividual variability in susceptibility remains poorly characterized for
environmental chemicals such as tetrachloroethylene (PERC). Development of population …

Hollow molecularly imprinted microspheres made by w/o/w double Pickering emulsion polymerization stabilized by graphene oxide quantum dots targeted for …

B Hosseinzadeh, N Nikfarjam, SH Kazemi - Colloids and Surfaces A …, 2021 - Elsevier
A double Pickering emulsion was designed to fabricate hollow imprinted microspheres (H-
IMMs) for the detection of l-Cysteine (l-Cys). In aw 1/o/w 2 double emulsion, the main o/w 2 …

Comparative analysis of metabolism of trichloroethylene and tetrachloroethylene among mouse tissues and strains

YS Luo, NH Hsieh, VY Soldatow, WA Chiu, I Rusyn - Toxicology, 2018 - Elsevier
Trichloroethylene (TCE) and tetrachloroethylene (PCE) are structurally similar chemicals
that are metabolized through oxidation and glutathione conjugation pathways. Both …

Nonalcoholic fatty liver disease is a susceptibility factor for perchloroethylene-induced liver effects in mice

JA Cichocki, S Furuya, YS Luo, Y Iwata… - Toxicological …, 2017 - academic.oup.com
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent pathological liver condition in
developed countries. NAFLD results in severe alterations in liver function, including …