Behavioral and neurobiological mechanisms of pavlovian and instrumental extinction learning
This article reviews the behavioral neuroscience of extinction, the phenomenon in which a
behavior that has been acquired through Pavlovian or instrumental (operant) learning …
behavior that has been acquired through Pavlovian or instrumental (operant) learning …
Deep brain stimulation for the treatment of drug addiction
Drug addiction represents a significant public health concern that has high rates of relapse
despite optimal medical therapy and rehabilitation support. New therapies are needed, and …
despite optimal medical therapy and rehabilitation support. New therapies are needed, and …
The application of deep brain stimulation in the treatment of psychiatric disorders
Deep brain stimulation (DBS) is a last-resort treatment for neurological and psychiatric
disorders that are refractory to standard treatment. Over the last decades, the progress of …
disorders that are refractory to standard treatment. Over the last decades, the progress of …
Environmental, genetic and epigenetic contributions to cocaine addiction
RC Pierce, B Fant, SE Swinford-Jackson… - …, 2018 - nature.com
Decades of research on cocaine has produced volumes of data that have answered many
important questions about the nature of this highly addictive drug. Sadly, none of this …
important questions about the nature of this highly addictive drug. Sadly, none of this …
Circuit selectivity in drug versus natural reward seeking behaviors
Substance use disorder (SUD) is characterized, in part by behavior biased toward drug use
and away from natural sources of reward (eg, social interaction, food, sex). The …
and away from natural sources of reward (eg, social interaction, food, sex). The …
Chemogenetic modulation of accumbens direct or indirect pathways bidirectionally alters reinstatement of heroin-seeking in high-but not low-risk rats
TJ O'Neal, MN Nooney, K Thien… - …, 2020 - nature.com
Opioid addiction has been declared a public health emergency, with fatal overdoses
following relapse reaching epidemic proportions and disease-associated costs continuing to …
following relapse reaching epidemic proportions and disease-associated costs continuing to …
Deep brain stimulation in drug addiction treatment: research progress and perspective
R Chang, J Peng, Y Chen, H Liao, S Zhao… - Frontiers in …, 2022 - frontiersin.org
Drug addiction is a chronic psychiatric disorder characterized by compulsive drug-seeking
and drug-using behavior, and a tremendous socioeconomic burden to society. Current …
and drug-using behavior, and a tremendous socioeconomic burden to society. Current …
A wide range of Deep Brain Stimulation of the nucleus accumbens shell time independently reduces the extinction period and prevents the reinstatement of …
K Eskandari, M Fattahi, E Riahi, R Khosrowabadi… - Life Sciences, 2023 - Elsevier
Methamphetamine (METH) addiction is a significant public health issue, and standard
medical therapies are often not curative. Deep Brain Stimulation (DBS) has recently shown …
medical therapies are often not curative. Deep Brain Stimulation (DBS) has recently shown …
Ventral tegmental area afferents and drug-dependent behaviors
Drug-related behaviors in both humans and rodents are commonly thought to arise from
aberrant learning processes. Preclinical studies demonstrate that the acquisition and …
aberrant learning processes. Preclinical studies demonstrate that the acquisition and …
Brain stimulation in eating disorders: state of the art and future perspectives
The management of eating disorders (EDs) is still difficult and few treatments are effective.
Recently, several studies have described the important contribution of non-invasive brain …
Recently, several studies have described the important contribution of non-invasive brain …