The incidence and prevalence of Huntington's disease (HD) based on a systematic review
and meta‐analysis of 20 studies published from 1985 to 2010 was estimated at 0.38 per …

Simple Summary Neurodegenerative diseases represent an important cause of morbidity
and mortality worldwide. Existing therapeutic options are limited and focus mostly on …

Introduction: Parkinson's disease (PD) is a neurodegenerative disorder affecting a
substantial proportion of the elderly Cypriot population. The objective of this study was to …

Background Multimorbidity is defined as the co-existence of two or more chronic conditions.
As life expectancy is increasing so does the prevalence of multimorbidity. Our aim was to …

Background There is great heterogeneity on geographic and temporary Huntington disease
(HD) epidemiological estimates. Most research studies of rare diseases, including HD, use …

Huntington's disease (HD) is a rare progressive neurodegenerative disease characterised
by autosomal dominant inheritance. The past decade saw a growing interest in the …

Background: Huntington's disease (HD) is a rare, genetic, neurodegenerative disease.
Obtaining population-level data on epidemiology and disease management is challenging …

We describe FoundHaplo, a novel identity-by-descent algorithm designed to identify
individuals with known, untyped, disease-causing variants using only SNP array data …

Neurodegenerative diseases are an increasing cause of global morbidity and mortality.
They occur in the central nervous system (CNS) and lead to functional and mental …

Background: The purpose of this study was to analyze optical coherence tomography (OCT)
parameters of the choroid and retina in subjects with pre-manifest and manifest Huntington's …