Diagnostic and prognostic epigenetic biomarkers in cancer

P Costa-Pinheiro, D Montezuma, R Henrique… - …, 2015 - Taylor & Francis
Growing cancer incidence and mortality worldwide demands development of accurate
biomarkers to perfect detection, diagnosis, prognostication and monitoring. Urologic …

[HTML][HTML] Role of let-7 family microRNA in breast cancer

CK Thammaiah, S Jayaram - Non-coding RNA research, 2016 - Elsevier
Metastasis and resistance to therapy significantly contribute to cancer-related deaths.
Growing body of evidence suggest that altered expression of microRNAs (miRNAs) is one of …

Predicting microRNA-disease associations based on improved microRNA and disease similarities

W Lan, J Wang, M Li, J Liu, FX Wu… - IEEE/ACM transactions …, 2016 - ieeexplore.ieee.org
MicroRNAs (miRNAs) are a type of non-coding RNAs with about~ 22nt nucleotides.
Increasing evidences have shown that miRNAs play critical roles in many human diseases …

MicroRNA-494 inhibits breast cancer progression by directly targeting PAK1

MN Zhan, XT Yu, J Tang, CX Zhou, CL Wang… - Cell death & …, 2018 - nature.com
MicroRNA (miRNA) is involved in the progression and metastasis of diverse human cancers,
including breast cancer, as strong evidence has been found that miRNAs can act as …

[HTML][HTML] Comprehensive analysis of microRNA expression profile in malignant glioma tissues

M Piwecka, K Rolle, A Belter, AM Barciszewska… - Molecular …, 2015 - Elsevier
Malignant gliomas represent the most devastating group of brain tumors in adults, among
which glioblastoma multiforme (GBM) exhibits the highest malignancy rate. Despite …

A potential prognostic long non-coding RNA signature to predict metastasis-free survival of breast cancer patients

J Sun, X Chen, Z Wang, M Guo, H Shi, X Wang… - Scientific reports, 2015 - nature.com
Long non-coding RNAs (lncRNAs) have been implicated in a variety of biological processes
and dysregulated lncRNAs have demonstrated potential roles as biomarkers and …

[HTML][HTML] Dysregulation and functional roles of miR-183-96-182 cluster in cancer cell proliferation, invasion and metastasis

Y Ma, AJ Liang, YP Fan, YR Huang, XM Zhao, Y Sun… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Previous studies have reported aberrant expression of the miR-183-96-182 cluster in a
variety of tumors, which indicates its' diagnostic or prognostic value. However, a key …

A nine-miRNA signature as a potential diagnostic marker for breast carcinoma: An integrated study of 1,110 cases

DD Xiong, J Lv, KL Wei, ZB Feng… - Oncology …, 2017 - spandidos-publications.com
Growing evidence indicates that microRNAs (miRNAs) play critical roles in the initiation and
progression of breast carcinoma (BC) and are promising diagnostic biomarkers. In the …

ErbB-2 nuclear function in breast cancer growth, metastasis and resistance to therapy

PV Elizalde, RIC Russo, MF Chervo… - Endocrine-related …, 2016 - erc.bioscientifica.com
Approximately 15–20% of breast cancers (BC) show either membrane overexpression of
ErbB-2 (MErbB-2), a member of the ErbBs family of receptor tyrosine kinases, or ERBB2 …

Housekeeping genes for studies of plasma microRNA: A need for more precise standardization

J Rice, H Roberts, SN Rai, S Galandiuk - Surgery, 2015 - Elsevier
Introduction Plasma microRNAs (miRNAs) are promising biomarkers for many forms of
cancer in humans; however, a fundamental concern is the lack of standardization in current …