Ischemic heart disease (IHD) is the leading cause of disability and mortality worldwide.
Reactive oxygen species (ROS) have been shown to play key roles in the progression of …

The vascular endothelium has several important functions, including hemostasis. The
homeostasis of hemostasis is based on a fine balance between procoagulant and …

An effective nanotherapeutic transport from the vasculature to the tumour is crucial for
cancer treatment with minimal side effects. Here we demonstrate that, in addition to the …

Tumour microenvironment hinders nanoparticle transport deep into the tissue precluding
thorough treatment of solid tumours and metastatic nodes. We introduce an anticancer drug …

Endothelial cells throughout the body are heterogeneous, and this is tightly linked to the
specific functions of organs and tissues. Heterogeneity is already determined from …

A long-standing goal of nanomedicine is to improve a drug's benefit by loading it into a
nanocarrier that homes solely to a specific target cell and organ. Unfortunately, nanocarriers …

Endothelial cells play critical roles in circulatory homeostasis and are also the gateway to
the major organs of the body. Dysfunction, injury, and gene expression profiles of these cells …

Although several nanomedicines got clinical approval over the past two decades, the clinical
translation rate is relatively small so far. There are many post-surveillance withdrawals of …

Endothelial cell dysfunction occurs in a variety of acute and chronic pulmonary diseases
including pulmonary hypertension, viral and bacterial pneumonia, bronchopulmonary …

Atherosclerosis, a chronic disease associated with metabolism, poses a significant risk to
human well‐being. Currently, existing treatments for atherosclerosis lack sufficient efficiency …