In vitro antimicrobial, physicochemical, pharmacokinetics and molecular docking studies of benzoyl uridine esters against SARS-CoV-2 main protease
Different esters were found potential against microorganisms, and could be a better choice
to solve the multidrug resistant (MDR) pathogenic global issue due to their improved …
to solve the multidrug resistant (MDR) pathogenic global issue due to their improved …
Langmuir monolayers provide an effective strategy for studying molecular Recognition of nucleobases using alkylated nucleotides
FA Moreira, JFB Escobar, C Giordani… - Colloids and Surfaces B …, 2024 - Elsevier
Molecular Recognition in nucleotides is crucial for medicine, underpinning precise
interactions in genetic replication and therapy. Alkylated nucleotides, in particular, play a key …
interactions in genetic replication and therapy. Alkylated nucleotides, in particular, play a key …
Interaction of 3′, 4′, 6′-trimyristoyl-uridine derivative as potential anticancer drug with phospholipids of tumorigenic and non-tumorigenic cells
LFG Salis, GN Jaroque, JFB Escobar, C Giordani… - Applied Surface …, 2017 - Elsevier
Investigating the mechanism of action of drugs whose pharmaceutical activity is associated
with cell membranes is fundamental to comprehending the biochemical and biophysical …
with cell membranes is fundamental to comprehending the biochemical and biophysical …
Exploring the physicochemical properties of the integration of Tristearoyl uridine in Langmuir monolayers: An approach to cell membrane modeling for prodrugs
FA Moreira, JFB Escobar, C Giordani, L Caseli - Biophysical Chemistry, 2024 - Elsevier
Understanding the mechanisms by which drugs interact with cell membranes is crucial for
unraveling the underlying biochemical and biophysical processes that occur on the surface …
unraveling the underlying biochemical and biophysical processes that occur on the surface …
Synthesis and cytotoxic activity of per-acetylated and halogenated derivatives of nucleosides in breast cancer cells
JF Berrío Escobar, MH Pastrana Restrepo… - 2017 - bibliotecadigital.udea.edu.co
Objectives. To make the synthesis of halogenated derivatives on the nitrogenous base and
their respective acyl ester and amide type derivatives for all hydroxyl and amine groups of …
their respective acyl ester and amide type derivatives for all hydroxyl and amine groups of …
Anomalous interaction of tri-acyl ester derivatives of uridine nucleoside with a l-α-dimyristoylphosphatidylcholine biomembrane model: a differential scanning …
JF Berrío Escobar… - Journal of Pharmacy …, 2019 - academic.oup.com
Objectives Uridine was conjugated with fatty acids to improve the drug lipophilicity and the
interaction with phospholipid bilayers. Methods The esterification reaction using …
interaction with phospholipid bilayers. Methods The esterification reaction using …
Synthesis of Analogs of Trans-Fagaramide and Their Cytotoxic Activity
MB Tomas, TC Shiao, PT Nguyen, S Bourgault… - Pharmaceutical …, 2018 - Springer
A series of 30 compounds were synthetized inspired by active trans-fagaramide structure
skeleton. On this synthetic platform, 18 compounds were achieved via Knoevenagel …
skeleton. On this synthetic platform, 18 compounds were achieved via Knoevenagel …
DSC studies on the interaction of lipophilic cytarabine prodrugs with DMPC multilamellar vesicles
JF Berrio Escobar, DM Marquez Fernandez… - Journal of Thermal …, 2019 - Springer
Abstract Cytarabine (1-β-d-arabinofuranosylcytosine, Ara-C), a pyrimidine nucleoside
analogue, is used for the treatment of both acute and chronic myeloblastic leukemias and …
analogue, is used for the treatment of both acute and chronic myeloblastic leukemias and …
[HTML][HTML] Síntesis y evaluación citotoxica de derivados halogenados y peracetylados de nucleósidos en celulas de cáncer de mama
JF Berrío Escobar, MH Pastrana Restrepo… - Ars Pharmaceutica …, 2017 - SciELO Espana
Objectives: To make the synthesis of halogenated derivatives on the nitrogenous base and
their respective acyl ester and amide type derivatives for all hydroxyl and amine groups of …
their respective acyl ester and amide type derivatives for all hydroxyl and amine groups of …