Initiation and development of cancer depend on multiple factors that mutations in genes and
epigenetic level can be considered as important drivers. Epigenetic factors include a large …

As a substrate and major effector of the mammalian target of rapamycin complex 1
(mTORC1), the biological functions of ribosomal protein S6 kinase (S6K) have been …

CD4+ T cells play a notable role in immune protection at different stages of life. During
aging, the interaction between the body's internal and external environment and CD4+ T …

Objective Oral cancer is the sixteenth most prevalent cancer in the world and the third-most
in India. Despite of several treatment modalities, the cure rate of oral cancer is still low due to …

Purpose Resistance to chemotherapy and radiotherapy is the primary cause of a poor
prognosis in oncological patients. Researchers identified many possible mechanisms …

Head and neck squamous cell carcinoma ranks seventh in incidence of malignant tumours
in the world. Although there are treatments including surgery, radiotherapy and …

Dynamic alterations in cellular phenotypes during cancer progression are attributed to a
phenomenon known as 'lineage plasticity'. This process is associated with therapeutic …

Background Glycolytic metabolic reprogramming is a phenomenon in which cells undergo
altered metabolic patterns during malignant transformation, mainly involving various aspects …

Simple Summary Although many therapies have been applied in oral squamous cell
carcinoma, these therapies are still unsatisfactory. Recently, the mitochondrial role in oral …

Abstract Background Circular RNAs (circRNAs) belong to a class of covalently closed single
stranded RNAs that have been implicated in cancer progression. Former investigations …