For the last two decades, researchers have placed hopes in a new era in which a
combination of reperfusion and neuroprotection would revolutionize the treatment of stroke …

Obesity, is an increasingly global public health problem associated complications. However,
the proven anti-obesity agents are inefficient with adverse side effects; hence attention is …

Objective To systematically investigate causal relationships between obesity and
cerebrovascular disease and the extent to which hypertension and hyperglycemia mediate …

Obesity is a predominant risk factor in ischemic stroke and is commonly comorbid with it.
Pathologies following these conditions are associated with systemic and local inflammation …

Ischemic stroke is a highly complex and devastating neurological disease. The sudden loss
of blood flow to a brain region due to an ischemic insult leads to severe damage to that area …

Metabolic disorders related to obesity and type 2 diabetes are associated with aggravated
cerebrovascular damages during stroke. In particular, hyperglycemia alters redox and …

Objective In this study, we aimed to determine whether insulin resistance is associated with
clinical outcomes after acute ischemic stroke. Methods We enrolled 4,655 patients with …

Introduction: Most ischemic strokes develop as a result of atherosclerosis, in which
inflammation plays a key role. The synthesis cascade of proinflammatory mediators …

Historically, obesity has been identified as one of the most important risk factors for
developing cardiovascular diseases including stroke; however, a theory called “The Obesity …

Obesity is well-established as a common comorbidity in ischemic stroke. The increasing
evidence has revealed that it also associates with the exacerbation of brain pathologies …