[HTML][HTML] Nanotechnology in cancer diagnosis and treatment

N Alrushaid, FA Khan, EA Al-Suhaimi, A Elaissari - Pharmaceutics, 2023 - mdpi.com
Traditional cancer diagnosis has been aided by the application of nanoparticles (NPs),
which have made the process easier and faster. NPs possess exceptional properties such …

[HTML][HTML] Optimization of the hemolysis assay for the assessment of cytotoxicity

IP Sæbø, M Bjørås, H Franzyk, E Helgesen… - International journal of …, 2023 - mdpi.com
In vitro determination of hemolytic properties is a common and important method for
preliminary evaluation of cytotoxicity of chemicals, drugs, or any blood-contacting medical …

[HTML][HTML] The therapeutic efficacy of dendrimer and micelle formulations for breast cancer treatment

S Alven, BA Aderibigbe - Pharmaceutics, 2020 - mdpi.com
Breast cancer is among the most common types of cancer in women and it is the cause of a
high rate of mortality globally. The use of anticancer drugs is the standard treatment …

[HTML][HTML] Starburst pamam dendrimers: Synthetic approaches, surface modifications, and biomedical applications

R Kharwade, S More, A Warokar, P Agrawal… - Arabian Journal of …, 2020 - Elsevier
Dendrimers are having novel three dimensional, synthetic hyperbranched, nano-polymeric
structure. Among all of the dendrimers, Poly-amidoamine (PAMAM) dendrimer are used …

Recent advances in multifunctional dendrimer-based nanoprobes for breast cancer theranostics

P Kesharwani, R Chadar, R Shukla… - Journal of …, 2022 - Taylor & Francis
Breast cancer (BC) undoubtedly is one of the most common type of cancers amongst
women, which causes about 5 million deaths annually. The treatments and diagnostic …

[HTML][HTML] β-lapachone suppresses tumour progression by inhibiting epithelial-to-mesenchymal transition in NQO1-positive breast cancers

Y Yang, X Zhou, M Xu, J Piao, Y Zhang, Z Lin… - Scientific reports, 2017 - nature.com
NQO1 is a FAD-binding protein that can form homodimers and reduce quinones to
hydroquinones, and a growing body of evidence currently suggests that NQO1 is …

[HTML][HTML] Delivery systems for mitochondrial gene therapy: a review

R Faria, P Boisguérin, Â Sousa, D Costa - Pharmaceutics, 2023 - mdpi.com
Mitochondria are membrane-bound cellular organelles of high relevance responsible for the
chemical energy production used in most of the biochemical reactions of cells. Mitochondria …

Recent advances in novel drug delivery systems and approaches for management of breast cancer: A comprehensive review

U Hani, M Rahamathulla, RA Osmani, HY Kumar… - Journal of Drug Delivery …, 2020 - Elsevier
Breast Cancer (BC) is a carcinoma of breast tissues, the major recurrent cancer in women
and also the foremost cause of death with approximate 5 million annual deaths worldwide …

Radiation‐sensitive dendrimer‐based drug delivery system

SY Wu, HY Chou, CH Yuh, SL Mekuria… - Advanced …, 2018 - Wiley Online Library
Combination of chemotherapy and radiotherapy is used to enhance local drug delivery
while reducing off‐target tissue effects. Anticancer drug doxorubicin (DOX) is loaded into l …

[HTML][HTML] Effects of the surface charge of polyamidoamine dendrimers on cellular exocytosis and the exocytosis mechanism in multidrug-resistant breast cancer cells

J Zhang, M Li, M Wang, H Xu, Z Wang, Y Li… - Journal of …, 2021 - Springer
Background Polyamidoamine (PAMAM) dendrimer applications have extended from tumor
cells to multidrug-resistant tumor cells. However, their transportation in multidrug-resistant …