Chemotherapeutics occupy a pivotal role in the medication of different types of cancers, but
the prevalence and mortality rates of cancer remain high. The drug resistance and low …

This review article proposes a comprehensive report of the design strategies engaged in the
development of various sulfur‐bearing cytotoxic agents. The outcomes of various studies …

Pyrazole derivatives, as a class of heterocyclic compounds, possess unique chemical
structures that confer them with a broad spectrum of pharmacological activities. They have …

Chemotherapy is an important therapeutic approach for the treatment of cancer. Currently,
many anticancer drugs are available in the market that plays an important role in cancer …

Thiazole and oxazole are compounds with a heterocyclic nucleus that have attracted the
attention of medicinal chemistry due to the great variety of biological activities that they …

This review-based study presents the anticancer potential of pyrazole-based copper
complexes, aiming to evaluate their mechanistic action at the molecular level and find …

An approach in modern medicinal chemistry to discover novel bioactive compounds is by
mimicking diverse complementary pharmacophores. In extension of this strategy, a new …

The development of new small molecules from known structural motifs through molecular
hybridization is one of the trends in drug discovery. In this connection, we have combined …

Cancer is one of the major causes of mortality and morbidity worldwide. Substantial
research efforts have been made to develop new chemical entities with improved anticancer …

In the past five years, our team had been committed to click chemistry research, exploring
the biological activity of 1, 2, 3-triazole by synthesizing different target inhibitors. In this study …