Approaches to expand the conventional toolbox for discovery and selection of antibodies with drug-like physicochemical properties
Antibody drugs should exhibit not only high-binding affinity for their target antigens but also
favorable physicochemical drug-like properties. Such drug-like biophysical properties are …
favorable physicochemical drug-like properties. Such drug-like biophysical properties are …
Synthetic Cells from Droplet‐Based Microfluidics for Biosensing and Biomedical Applications
K Ngocho, X Yang, Z Wang, C Hu, X Yang, H Shi… - Small, 2024 - Wiley Online Library
Synthetic cells function as biological mimics of natural cells by mimicking salient features of
cells such as metabolism, response to stimuli, gene expression, direct metabolism, and high …
cells such as metabolism, response to stimuli, gene expression, direct metabolism, and high …
Enhancing Protein Solubility via Glycosylation: From Chemical Synthesis to Machine Learning Predictions
B Ma, H Chen, J Gong, W Liu, X Wei, Y Zhang… - …, 2024 - ACS Publications
Glycosylation is a valuable tool for modulating protein solubility; however, the lack of reliable
research strategies has impeded efficient progress in understanding and applying this …
research strategies has impeded efficient progress in understanding and applying this …