Biomarkers shared by frailty and sarcopenia in older adults: A systematic review and meta-analysis

A Picca, HJ Coelho-Junior, R Calvani, E Marzetti… - Ageing research …, 2022 - Elsevier
Background Physical frailty and sarcopenia show extensive clinical similarities. Whether
biomarkers exist that are shared by the two conditions is presently unclear. Methods We …

Secondary prevention through comprehensive cardiovascular rehabilitation: From knowledge to implementation. 2020 update. A position paper from the Secondary …

M Ambrosetti, A Abreu, U Corrà… - European journal of …, 2021 - academic.oup.com
Secondary prevention through comprehensive cardiac rehabilitation has been recognized
as the most cost-effective intervention to ensure favourable outcomes across a wide …

Development and validation of a Hospital Frailty Risk Score focusing on older people in acute care settings using electronic hospital records: an observational study

T Gilbert, J Neuburger, J Kraindler, E Keeble, P Smith… - The Lancet, 2018 - thelancet.com
Background Older people are increasing users of health care globally. We aimed to
establish whether older people with characteristics of frailty and who are at risk of adverse …

Efficacy and safety of dapagliflozin according to frailty in heart failure with reduced ejection fraction: a post hoc analysis of the DAPA-HF trial

JH Butt, P Dewan, B Merkely, J Belohlávek… - Annals of internal …, 2022 - acpjournals.org
Background: Frailty may modify the risk− benefit profile of certain treatments, and frail
patients may have reduced tolerance to treatments. Objective: To investigate the efficacy of …

Relationship of body mass index with frailty and all-cause mortality among middle-aged and older adults

K Jayanama, O Theou, J Godin, A Mayo, L Cahill… - BMC medicine, 2022 - Springer
Background Parallel to growth of aging and obese populations, the prevalence of metabolic
diseases is rising. How body mass index (BMI) relates to frailty and mortality across frailty …

Efficacy and safety of dapagliflozin according to frailty in patients with heart failure: a prespecified analysis of the DELIVER trial

JH Butt, PS Jhund, J Belohlávek, RA De Boer… - Circulation, 2022 - Am Heart Assoc
Background: Frailty is increasing in prevalence. Because patients with frailty are often
perceived to have a less favorable risk/benefit profile, they may be less likely to receive new …

Frailty measurement in research and clinical practice: a review

E Dent, P Kowal, EO Hoogendijk - European journal of internal medicine, 2016 - Elsevier
One of the leading causes of morbidity and premature mortality in older people is frailty.
Frailty occurs when multiple physiological systems decline, to the extent that an individual's …

Frailty and cancer: implications for oncology surgery, medical oncology, and radiation oncology

CG Ethun, MA Bilen, AB Jani, SK Maithel… - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE The concept of frailty has become increasingly
recognized as one of the most important issues in health care and health outcomes and is of …

An overview of co-morbidities and the development of pressure ulcers among older adults

E Jaul, J Barron, JP Rosenzweig, J Menczel - BMC geriatrics, 2018 - Springer
Background The prevalence of pressure ulcers particularly in the frail older adult population
continues to be high and very costly especially in those suffering from chronic diseases and …

Sex differences in frailty: a systematic review and meta-analysis

EH Gordon, NM Peel, M Samanta, O Theou… - Experimental …, 2017 - Elsevier
Background It is a well-described clinical phenomenon that females live longer than males,
yet tend to experience greater levels of co-morbidity and disability. Females can therefore be …