Melatonin is ubiquitous molecule with wide distribution in nature and is produced by many
living organisms. In human beings, pineal gland is the major site for melatonin production …

During the past decade, research has revealed that the vast community of micro-organisms
that inhabit the gut—known as the gut microbiota—is intricately linked to human health and …

Genetics studies of autism spectrum disorder (ASD) have identified several risk genes that
are key regulators of synaptic plasticity. Indeed, many of the risk genes that have been …

Increasing evidence suggests that synaptic dysfunction is a key pathophysiological hallmark
in neurodegenerative disorders, including Alzheimer's disease. Understanding the role of …

Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders with a high
prevalence and impact on society. ASDs are characterized by deficits in both social behavior …

Ferroptosis is a form of regulated cell death that is mainly triggered by iron-dependent lipid
peroxidation. A growing body of evidence suggests that ferroptosis is involved in the …

Neurotrophins and their receptors modulate multiple signalling pathways to regulate
neuronal survival and to maintain axonal and dendritic networks and synaptic plasticity …

In the last 30 years, twin studies have indicated a strong genetic contribution to Autism
Spectrum Disorders (ASD). The heritability of ASD is estimated to be 50%, mostly captured …

Abnormal brain-derived neurotrophic factor (BDNF) signaling seems to have a central role in
the course and development of various neurological and psychiatric disorders. In addition …

N-acetyl serotonin (NAS) as a melatonin precursor has neuroprotective actions.
Nonetheless, it is not clarified how NAS protects neuronal cells against oxidative stress …