A gap exists between guidelines and real-world clinical practice for the management and
treatment of chronic obstructive pulmonary disease (COPD). Although this has narrowed in …

As cannabis use increases, physicians need to be familiar with the effects of both cannabis
and tobacco on the lungs. However, there have been very few long-term studies of cannabis …

Despite the availability of guideline recommendations, diagnostic confusion between COPD
and asthma appears common, and often it is very difficult to decide whether the obstruction …

Rationale: The Global Lung Initiative (GLI) provides age-appropriate criteria for establishing
spirometric impairment, including mild, moderate, and severe chronic obstructive pulmonary …

Rationale: The American Thoracic Society (ATS)/European Respiratory Society defines a
positive bronchodilator response (BDR) by a composite of BDR in either forced expiratory …

Rationale: In aging populations, the commonly used Global Initiative for Chronic Obstructive
Lung Disease (GOLD) may misclassify normal spirometry as respiratory impairment (airflow …

Current epidemiologic practice evaluates COPD based on self-reported symptoms of
chronic bronchitis, self-reported physician-diagnosed COPD, spirometry confirmed airflow …

Background: Although comorbidity is important in multiple sclerosis (MS), few validated
methods for its assessment exist. We validated and applied administrative case definitions …

Background Little is known on the association between HIV infection and chronic obstructive
pulmonary disease (COPD) in sub-Saharan Africa. We assessed the prevalence and …

Background Bronchodilator responsiveness (BDR) in obstructive lung disease varies over
time and may be associated with distinct clinical features. Research Question Is consistent …