Celiac disease: a review of current concepts in pathogenesis, prevention, and novel therapies

JA Tye-Din, HJ Galipeau, D Agardh - Frontiers in pediatrics, 2018 - frontiersin.org
Our understanding of celiac disease and how it develops has evolved significantly over the
last half century. Although traditionally viewed as a pediatric illness characterized by …

Novel players in coeliac disease pathogenesis: role of the gut microbiota

EF Verdu, HJ Galipeau, B Jabri - Nature Reviews Gastroenterology & …, 2015 - nature.com
Several studies point towards alteration in gut microbiota composition and function in
coeliac disease, some of which can precede the onset of disease and/or persist when …

Celiac disease: an immunological jigsaw

B Meresse, G Malamut, N Cerf-Bensussan - Immunity, 2012 - cell.com
Celiac disease (CD) is a chronic enteropathy induced by dietary gluten in genetically
predisposed people. The keystone of CD pathogenesis is an adaptive immune response …

Co-factors, microbes, and immunogenetics in celiac disease to guide novel approaches for diagnosis and treatment

EF Verdu, D Schuppan - Gastroenterology, 2021 - Elsevier
Celiac disease (CeD) is a frequent immune-mediated disease that affects not only the small
intestine but also many extraintestinal sites. The role of gluten proteins as dietary triggers …

New Developments in celiac disease treatment

MV Machado - International journal of molecular sciences, 2023 - mdpi.com
Celiac disease (CD) is a common autoimmune disease affecting around 1% of the
population. It consists of an immune-mediated enteropathy, triggered by gluten exposure in …

Association between inflammatory bowel diseases and celiac disease: a systematic review and meta-analysis

MI Pinto-Sanchez, CL Seiler, N Santesso, A Alaedini… - Gastroenterology, 2020 - Elsevier
Background & Aims There is controversy over the association between celiac disease (CeD)
and inflammatory bowel diseases (IBD). We performed a systematic review and meta …

Decreased Risk of Celiac Disease in Patients With Helicobacter pylori Colonization

B Lebwohl, MJ Blaser, JF Ludvigsson… - American journal of …, 2013 - academic.oup.com
The prevalence of celiac disease (CD) has increased in recent decades without a clear
explanation. The “hygiene hypothesis” theorizes that decreased exposure to bacterial …

[HTML][HTML] Intestinal microbiota modulates gluten-induced immunopathology in humanized mice

HJ Galipeau, JL McCarville, S Huebener… - The American journal of …, 2015 - Elsevier
Celiac disease (CD) is an immune-mediated enteropathy triggered by gluten in genetically
susceptible individuals. The recent increase in CD incidence suggests that additional …

Non-celiac gluten sensitivity: literature review

P Mansueto, A Seidita, A D'Alcamo… - Journal of the American …, 2014 - Taylor & Francis
Background: A significant percentage of the general population report problems caused by
wheat and/or gluten ingestion, even though they do not have celiac disease (CD) or wheat …

Interplay between gluten, HLA, innate and adaptive immunity orchestrates the development of coeliac disease

J Voisine, V Abadie - Frontiers in Immunology, 2021 - frontiersin.org
Several environmental, genetic, and immune factors create a “perfect storm” for the
development of coeliac disease: the antigen gluten, the strong association of coeliac …