Consensus guidelines for the use and interpretation of angiogenesis assays

P Nowak-Sliwinska, K Alitalo, E Allen, A Anisimov… - Angiogenesis, 2018 - Springer
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

Bioactive glasses: sprouting angiogenesis in tissue engineering

S Kargozar, F Baino, S Hamzehlou, RG Hill… - Trends in …, 2018 - cell.com
The biggest strategic challenge for tissue engineering is the development of efficient
vascularized networks in engineered tissues and organs. Bioactive glasses (BGs) are potent …

[HTML][HTML] Impairment of an endothelial NAD+-H2S signaling network is a reversible cause of vascular aging

A Das, GX Huang, MS Bonkowski, A Longchamp, C Li… - Cell, 2018 - cell.com
A decline in capillary density and blood flow with age is a major cause of mortality and
morbidity. Understanding why this occurs is key to future gains in human health. NAD …

Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma

T Bald, T Quast, J Landsberg, M Rogava, N Glodde… - Nature, 2014 - nature.com
Intermittent intense ultraviolet (UV) exposure represents an important aetiological factor in
the development of malignant melanoma. The ability of UV radiation to cause tumour …

Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation

C Coletta, A Papapetropoulos… - Proceedings of the …, 2012 - National Acad Sciences
Hydrogen sulfide (H2S) is a unique gasotransmitter, with regulatory roles in the
cardiovascular, nervous, and immune systems. Some of the vascular actions of H2S …

Plastic roles of pericytes in the blood–retinal barrier

DY Park, J Lee, J Kim, K Kim, S Hong, S Han… - Nature …, 2017 - nature.com
The blood–retinal barrier (BRB) consists of tightly interconnected capillary endothelial cells
covered with pericytes and glia, but the role of the pericytes in BRB regulation is not fully …

Exosomes secreted by hiPSC-derived cardiac cells improve recovery from myocardial infarction in swine

L Gao, L Wang, Y Wei, P Krishnamurthy… - Science translational …, 2020 - science.org
Cell therapy treatment of myocardial infarction (MI) is mediated, in part, by exosomes
secreted from transplanted cells. Thus, we compared the efficacy of treatment with a mixture …

Injectable hydrogel with slow degradability composed of gelatin and hyaluronic acid cross-linked by Schiff's base formation

T Hozumi, T Kageyama, S Ohta, J Fukuda… - …, 2018 - ACS Publications
We developed an injectable gelatin/hyaluronic acid hydrogel with slow degradability, which
consisted of carbohydrazide-modified gelatin (Gel-CDH) and hyaluronic acid monoaldehyde …

Laminar shear stress inhibits endothelial cell metabolism via KLF2-mediated repression of PFKFB3

A Doddaballapur, KM Michalik, Y Manavski… - … , and vascular biology, 2015 - Am Heart Assoc
Objective—Cellular metabolism was recently shown to regulate endothelial cell phenotype
profoundly. Whether the atheroprotective biomechanical stimulus elicited by laminar shear …

Glutamine fuels proliferation but not migration of endothelial cells

B Kim, J Li, C Jang, Z Arany - The EMBO journal, 2017 - embopress.org
Endothelial metabolism is a key regulator of angiogenesis. Glutamine metabolism in
endothelial cells (EC s) has been poorly studied. We used genetic modifications and 13C …