The steady progress in genome editing, especially genome editing based on the use of
clustered regularly interspaced short palindromic repeats (CRISPR) and programmable …

Somatic cell nuclear transfer (SCNT) has broad applications but is limited by low cloning
efficiency. In this review, we mainly focus on SCNT-mediated epigenetic reprogramming in …

The effectiveness of somatic cell nuclear transfer (SCNT) in mammals seems to be still
characterized by the disappointingly low rates of cloned embryos, fetuses, and progeny …

Mito-Q is a well-known mitochondria-specific superoxide scavenger. To our knowledge, the
effect of Mito-Q on buffalo oocyte maturation and developmental competency of cloned …

The term 'cloning'refers to the production of genetically identical individuals but has meant
different things throughout the history of science: a natural means of reproduction in …

To date, large‐scale use of multiple ovulation and embryo transfer (MOET) programmes in
ovine species is limited due to unpredictable results and high costs of hormonal stimulation …

Objective Protamine 1 (PRM1) is specific in sperm and plays essential roles in fertilization,
also a member of cancer testis antigen (CTA) family. This study aims to summarize the …

The large animal model has gradually become an essential part of preclinical research
studies, relating to exploring the disease pathological mechanism, genic function, pharmacy …

Alzheimer's disease (AD) is a devastating neurodegenerative disease with limited
therapeutic options. Cellular transplantation of healthy exogenic neurons to replace and …

Interspecies somatic cell nuclear transfer (iSCNT) has the capacity to rescue endangered
species, ethically produce human embryonic stem cells, and allow for more specific analysis …