Fluctuating selection and the determinants of genetic variation

OL Johnson, R Tobler, JM Schmidt, CD Huber - Trends in Genetics, 2023 - cell.com
Recent studies of cosmopolitan Drosophila populations have found hundreds to thousands
of genetic loci with seasonally fluctuating allele frequencies, bringing temporally fluctuating …

Rapid evolutionary change, constraints and the maintenance of polymorphism in natural populations of Drosophila melanogaster

A Glaser‐Schmitt, TJS Ramnarine… - Molecular …, 2024 - Wiley Online Library
Allele frequencies can shift rapidly within natural populations. Under certain conditions,
repeated rapid allele frequency shifts can lead to the long‐term maintenance of …

Genome‐wide transcriptomic changes reveal the genetic pathways involved in insect migration

T Doyle, E Jimenez‐Guri, WLS Hawkes… - Molecular …, 2022 - Wiley Online Library
Insects are capable of extraordinary feats of long‐distance movement that have profound
impacts on the function of terrestrial ecosystems. The ability to undertake these movements …

A cosmopolitan inversion facilitates seasonal adaptation in overwintering Drosophila

JCB Nunez, BA Lenhart, A Bangerter, CS Murray… - Genetics, 2024 - academic.oup.com
Fluctuations in the strength and direction of natural selection through time are a ubiquitous
feature of life on Earth. One evolutionary outcome of such fluctuations is adaptive tracking …

Enrichment of Hard Sweeps on the X Chromosome in Drosophila melanogaster

M Harris, NR Garud - Molecular Biology and Evolution, 2023 - academic.oup.com
The characteristic properties of the X chromosome, such as male hemizygosity and its
unique inheritance pattern, expose it to natural selection in a way that can be different from …

A Single Nucleotide Variant in the PPARγ-homolog Eip75B Affects Fecundity in Drosophila

KM Hoedjes, H Kostic, T Flatt… - Molecular biology and …, 2023 - academic.oup.com
Single nucleotide polymorphisms are the most common type of genetic variation, but how
these variants contribute to the adaptation of complex phenotypes is largely unknown …

On the resolution of sexual conflict over shared traits

TM Pennell, JE Mank, SH Alonzo… - Proceedings …, 2024 - royalsocietypublishing.org
Anisogamy, different-sized male and female gametes, sits at the heart of sexual selection
and conflict between the sexes. Sperm producers (males) and egg producers (females) of …

Pervasive tissue-, genetic background-, and allele-specific gene expression effects in Drosophila melanogaster

A Glaser-Schmitt, M Lemoine, M Kaltenpoth… - PLoS …, 2024 - journals.plos.org
The pervasiveness of gene expression variation and its contribution to phenotypic variation
and evolution is well known. This gene expression variation is context dependent, with …

Cis-regulatory polymorphism at fiz ecdysone oxidase contributes to polygenic evolutionary response to malnutrition in Drosophila

F Cavigliasso, M Savitsky, A Koval, B Erkosar… - Plos …, 2024 - journals.plos.org
We investigate the contribution of a candidate gene, fiz (fezzik), to complex polygenic
adaptation to juvenile malnutrition in Drosophila melanogaster. Experimental populations …

Enrichment of hard sweeps on the X chromosome compared to autosomes in six Drosophila species

M Harris, BY Kim, N Garud - Genetics, 2024 - academic.oup.com
The X chromosome, being hemizygous in males, is exposed one-third of the time increasing
the visibility of new mutations to natural selection, potentially leading to different evolutionary …