Modular Pathway Compartmentalization for Agroclavine Overproduction in Saccharomyces cerevisiae
N Wu, M Yao, W Xiao, T Dong, H Ma, X Du… - ACS Synthetic …, 2023 - ACS Publications
Agroclavine, which has anti-depressant activity and anti-Alzheimer effects, is the raw
material used to synthesize ergo-based drugs. Although the production of agroclavine from …
material used to synthesize ergo-based drugs. Although the production of agroclavine from …
General Access to Clavine Alkaloids via a Rhodium (I)‐Catalyzed Diastereoselective Hayashi‐Miyaura Reaction
G Leoni, F Bartoccini, G Piersanti - Advanced Synthesis & …, 2024 - Wiley Online Library
We report the development of the diastereoselective rhodium (I)‐catalyzed intramolecular
conjugate addition (Hayashi‐Miyaura reaction) of robust and easily handled 4 …
conjugate addition (Hayashi‐Miyaura reaction) of robust and easily handled 4 …
Synthesis and bioactivity of psilocybin analogues containing a stable carbon–phosphorus bond
M Vandevelde, A Simoens, B Vandekerckhove… - RSC Medicinal …, 2024 - pubs.rsc.org
Psilocybin analogues have been synthesized comprising a non-hydrolysable P–C bond to
evaluate the biological activity and the selectivity towards 5-HT2AR, 5-HT2BR and the TNAP …
evaluate the biological activity and the selectivity towards 5-HT2AR, 5-HT2BR and the TNAP …
Synthesis, Characterization of Indol-2-yl-Based NCO Pincer Rare-Earth Metal Alkyl Complexes and Their Catalytic Activity towards Hydroboration of Imines
X Yi, X Ji, Z Huang, F Wang, P Li, S Wang - Journal of Organometallic …, 2024 - Elsevier
The reactions of HL (L= 1-(CH 3 OCH 2 CH 2)-3-(Me 2 NCH 2)-C 8 H 4 N) with different
equivalent of the RE (CH 2 SiMe 3) 3 (THF) 2 produced a series of novel indol-2-yl-based …
equivalent of the RE (CH 2 SiMe 3) 3 (THF) 2 produced a series of novel indol-2-yl-based …
Literature-based drug–drug similarity for drug repurposing: impact of Medical Subject Headings term refinement and hierarchical clustering
SS Das, P Ranjan, IR Kunnakkattu - Future Medicinal Chemistry, 2022 - Taylor & Francis
Background: We describe herein, an improved procedure for drug repurposing based on
refined Medical Subject Headings (MeSH) terms and hierarchical clustering method …
refined Medical Subject Headings (MeSH) terms and hierarchical clustering method …