Targeting mycobacterial membranes and membrane proteins: Progress and limitations
Among the various bacterial infections, tuberculosis continues to hold center stage. Its
causative agent, Mycobacterium tuberculosis, possesses robust defense mechanisms …
causative agent, Mycobacterium tuberculosis, possesses robust defense mechanisms …
The Mycobacterium tuberculosis MmpL3 inhibitor MSU-43085 is active in a mouse model of infection
JT Williams, M Giletto, ER Haiderer, B Aleiwi… - Microbiology …, 2024 - Am Soc Microbiol
Addressing drug resistance in Mycobacterium tuberculosis (Mtb) requires the development
of new drugs with new targets. We previously identified 13 MmpL3 inhibitors from a screen …
of new drugs with new targets. We previously identified 13 MmpL3 inhibitors from a screen …
[图书][B] Chemical Biology and Genetic Studies Targeting the Mycobacterial Cell Envelope
JT Williams - 2021 - search.proquest.com
Mycobacterium tuberculosis is one of the leading causes of death due to a single infectious
pathogen. The evolution and spread of drug resistant strains requires new antibiotics to …
pathogen. The evolution and spread of drug resistant strains requires new antibiotics to …