Satellite glial cells (SGCs) closely envelop cell bodies of neurons in sensory, sympathetic
and parasympathetic ganglia. This unique organization is not found elsewhere in the …

The glial cell of the peripheral nervous system (PNS), the Schwann cell (SC), counts among
the most multifaceted cells of the body. During development, SCs secure neuronal survival …

Primary somatosensory neurons are specialized to transmit specific types of sensory
information through differences in cell size, myelination, and the expression of distinct …

Neurodegenerative diseases are characterized by the progressive loss of neurons and
intricate interactions between different cell types within the affected regions. Reliable …

Peripheral sensory neurons regenerate their axon after nerve injury to enable functional
recovery. Intrinsic mechanisms operating in sensory neurons are known to regulate nerve …

Peripheral nerves exist in a stable state in adulthood providing a rapid bidirectional
signaling system to control tissue structure and function. However, following injury …

Sensory neurons located in dorsal root ganglia (DRG) convey sensory information from
peripheral tissue to the brain. After peripheral nerve injury, sensory neurons switch to a …

Preclinical studies have identified glial cells as pivotal players in the genesis and
maintenance of neuropathic pain after nerve injury associated with diabetes, chemotherapy …

Astroglia are neural cells, heterogeneous in form and function, which act as supportive
elements of the central nervous system; astrocytes contribute to all aspects of neural …

Satellite glia are the major glial cells in sympathetic ganglia, enveloping neuronal cell
bodies. Despite this intimate association, the extent to which sympathetic functions are …